Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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Ectopic Cervical Thymic Tumor Misdiagnosed as a Thyroid Mass

갑상선 종괴로 오인된 이소성 경부 흉선 종양

  • Kim Jin-Soo (Department of Surgery, Yonsei University College of Medicine) ;
  • Chung Woung-Yoon (Department of Surgery, Yonsei University College of Medicine) ;
  • Hong Soon-Won (Department of Pathology, Yonsei University College of Medicine) ;
  • Yoon Jong-Ho (Department of Surgery, Yonsei University College of Medicine) ;
  • Chang Hang-Seok (Department of Surgery, Yonsei University College of Medicine) ;
  • Park Cheong-Soo (Department of Surgery, Yonsei University College of Medicine)
  • 김진수 (연세대학교 의과대학 외과학교실) ;
  • 정웅윤 (연세대학교 의과대학 외과학교실) ;
  • 홍순원 (연세대학교 의과대학 진단병리학교실) ;
  • 윤종호 (연세대학교 의과대학 외과학교실) ;
  • 장항석 (연세대학교 의과대학 외과학교실) ;
  • 박정수 (연세대학교 의과대학 외과학교실)
  • Published : 2003.05.01
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Abstract

Ectopic cervical thymic tumor, first described in 1941 by Boman, is a rare tumor of the neck displaying the same histologic features as mediastinal thymoma. It was classified into benign thymoma, invasive (or malignant) thymoma, thymic carcinoma histopathologically and clinically. The ectopic cervical thymic tumor is misdianosed as the thyroidal mass on radiologic examination and FNA cytology due to its rarity and unusual location. Recently, we have experienced two cases of ectopic cervical thymic tumor misdiagnosed as thyroid mass ; a case of thymic carcinoma;the other of invasive thymoma. So, we report these cases with review of the literature.

Keywords

References

  1. Boman K : On thymusfoeraendringar via myastemier. Nord Med. 1941 ; 10 : 1625-1634
  2. Chan JKC, Rosai J : Tumors of the neck showing thymic or related branchial pouch differentiation. A unifying concept. Hum Pathol. 1991 ; 22 : 349-367 https://doi.org/10.1016/0046-8177(91)90083-2
  3. Rosai J, Levine GD : Tumors of the Thymus. fascicle 13, series 2. Washington, DC : Armed Forces Institute of Pathology, 1976
  4. Levine GD, Rosai J : Thymic hyperplasia and neoplasia. A review ofcurrent concepts. Hum Pathol. 1978 ; 9 : 495-515 https://doi.org/10.1016/S0046-8177(78)80131-2
  5. Gilmour JR : The embryology of the parathyroid glands, the thymus and certain associated rudiments. J Pathol Bacteriol. 1937 ; 45 : 507-522 https://doi.org/10.1002/path.1700450304
  6. Gilmour JR : Some developmental abnormalities of the thymus and parathyroids. J Pathol Bacteriol. 1941 ; 52 : 213-218 https://doi.org/10.1002/path.1700520207
  7. Tao LC, Pearson FG, Cooper JD, Sanders DE, Weisbrod G, Donat EE : Cytopathology of thymoma. Acta Cytol. 1984 ; 28 : 165-170
  8. Oh YL, Ko YR, Ree HJ : Aspiration cytology of ectopic cervical thymoma mimicking a thyroid mass. Acta Cytol. 1998 ; 42 : 1167-1171 https://doi.org/10.1159/000332107
  9. Yamashita H, Murakami N, Noguchi S, et al : Cervical thymoma and incidence of cervical thymus. Acta Oathol Jpn. 1983 ; 33 : 189-194
  10. Justin MEM, Gurmeet R, Walley JT : Cervical thymoma. Arch Pathol Lab Med. 1986 ; 110 ; 354-357.
  11. Masaoka A, Monden Y, Nakahara K, Tanioka T : Follow-up study of thymomas with special reference to their clinical stages. Cancer. 1981 ; 48 : 2485-92 https://doi.org/10.1002/1097-0142(19811201)48:11<2485::AID-CNCR2820481123>3.0.CO;2-R
  12. Rosai J, Sobin LH : Histological typing of tumours of the thymus. International histological classification of tumours, 2nd edition. New York, Springer, 1999
  13. Fechner RE : Recurrence of noninvasive thymomas. Report of four cases and review of literature. Cancer. 1969 ; 23 : 1423 https://doi.org/10.1002/1097-0142(196906)23:6<1423::AID-CNCR2820230625>3.0.CO;2-M
  14. Rosenberg JC : Cancer. Principles and practice of oncology. In : Devita VT Jr; Hellman S, Rosengerg SA, et al : Neoplasms of the mediastinum. 2nd ed. Philadelphia: JB Lippincott Co, 1985 : 599
  15. Batata MA, Martini N, Huvos AG, Aguilar RI, Beattie EJ : Thymomas. Clinicopathologic features, therapy, and prognosis. Cancer. 1974 ; 34 : 389 https://doi.org/10.1002/1097-0142(197408)34:2<389::AID-CNCR2820340224>3.0.CO;2-Z
  16. Salyer WR, Eggleston JC : Thymoma. A clinical and pathological study of 65 cases. Cancer. 1974 ; 37 : 229 https://doi.org/10.1002/1097-0142(197601)37:1<229::AID-CNCR2820370133>3.0.CO;2-2
  17. LeGolvan DP, Abell MR : Thymomas. Cancer. 1977 ; 39 : 2142
  18. Wick MR, Weiland LH, Scheithauer BW, Bemats PE : Primary thymic carcinoma. Am J Surg Pathol. 1982 ; 6 : 613-630 https://doi.org/10.1097/00000478-198210000-00003
  19. Hsu CP, Chen CY, Chen CL, et al : Thymic carcinoma; ten years' experience in twenty patients. J Thorac Cardiovasc Surg. 1994 ; 107 : 615-20
  20. Legg MA, Brady WJ : Pathology and clinical behavior of thymomas. A survey of 51 cases. Cancer. 1965 ; 18 : 1131 https://doi.org/10.1002/1097-0142(196509)18:9<1131::AID-CNCR2820180914>3.0.CO;2-F
  21. Green JD, Forman WH : Responses if thymoma to steroids. Chest. 1974 ; 65 : 114
  22. Evans WK, Thompson DM, Simpson WJ, Phillips MJ : Combination chemotherapy in invasive thymoma. Role of COPP. Cancer. 1980 ; 46 : 1523 https://doi.org/10.1002/1097-0142(19801001)46:7<1523::AID-CNCR2820460705>3.0.CO;2-#
  23. Hu E, Levine J : Chemotherapy of malignant thymoma. Cases report and review ofliterature. Cancer. 1986 ; 57 : 1101 https://doi.org/10.1002/1097-0142(19860315)57:6<1101::AID-CNCR2820570606>3.0.CO;2-A