Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
권호 표지

Evaluation of the Response of Radiotherapy to Squamous Cell Carcinoma of the Head and Neck using $^{18}FDG-PET$

두경부 편평상피세포암종에서 $^{18}FDG-PET$을 이용한 방사선치료 반응평가

  • Lee Sang-Wook (Departments of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Ryu Jin-Sook (Departments of Neclear Medicine, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Yi Byong-Yong (Departments of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Kim Jong-Hoon (Departments of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Ahn Seung-Do (Departments of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Shin Seong-Soo (Departments of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Kim Sang-Yoon (Departments of Otorhinolaryngolog, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Nam Soon-Yuhl (Departments of Otorhinolaryngolog, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Song Si-Yeol (Departments of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Yoon Sang-Min (Departments of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Park Jin-Hong (Departments of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Kim Sung-Bae (Departments of Internal Medicine, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Kim Jae-Seung (Departments of Neclear Medicine, Asan Medical Center, College of Medicine, University of Ulsan)
  • 이상욱 (울산대학교 의과대학 서울아산병원 방사선종양학과) ;
  • 류진숙 (울산대학교 의과대학 서울아산병원 핵의학과) ;
  • 이병용 (울산대학교 의과대학 서울아산병원 방사선종양학과) ;
  • 김종훈 (울산대학교 의과대학 서울아산병원 방사선종양학과) ;
  • 안승도 (울산대학교 의과대학 서울아산병원 방사선종양학과) ;
  • 신성수 (울산대학교 의과대학 서울아산병원 방사선종양학과) ;
  • 김상윤 (울산대학교 의과대학 서울아산병원 이비인후과) ;
  • 남순열 (울산대학교 의과대학 서울아산병원 이비인후과) ;
  • 송시열 (울산대학교 의과대학 서울아산병원 방사선종양학과) ;
  • 윤상민 (울산대학교 의과대학 서울아산병원 방사선종양학과) ;
  • 박진홍 (울산대학교 의과대학 서울아산병원 방사선종양학과) ;
  • 김성배 (울산대학교 의과대학 서울아산병원 내과) ;
  • 김재승 (울산대학교 의과대학 서울아산병원 핵의학과)
  • Published : 2003.05.01
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Abstract

Purpose: To evaluate the efficacy of positron emission tomography with 2-[F-18] fluoro-2-deoxy-D-glucose in discrimination of response in the nasopharyngeal carcinoma patients who treated with radiotherapy. Methods and Materials: Twenty-four patients who underwent FDG-PET scan before and after radiotherapy for no disseminated head and neck carcinoma at the Asan Medical Center between August 2001 and September 2002 were evaluate by prospective analysis. First FDG-PET scan performed before radiotherapy within 1 month, and second FDG-PET scan performed 1 month after radiotherapy. FDG-PET images were analyzed by standard uptake value (SUV). Follow-up period was more than 6 months. Results: The pretreatment SUV was 3.4-14.0 (median: 6.0) and posttreatment SUV was ground level-7.7 (median: 2.0). The overall sensitivity and specicity of FDG-PET to evaluate residual tumors in the nasopharyngeal carcinoma patients were 94% and 94%. Conclusion: FDG-PET is effective in evaluation of radiation response in the nasopharyngeal carcinoma. We think that the timing of one month after finished radiotherapy FDG-PET scan was not too fast to evaluation of radiation response.

Keywords

References

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