Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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Significance of Fine-Needle Aspiration Cytology and Frozen Section Biopsy in Thyroid Nodules

갑상선 결절에서 세침흡인검사와 동결조직검사의 의의

  • Song Dal-Won (Department of Otolaryngology, School of Medicine, Keimyung University) ;
  • Sohn Su-Gil (Department of Otolaryngology, School of Medicine, Keimyung University) ;
  • Choi Jong-Won (Department of Otolaryngology, School of Medicine, Keimyung University) ;
  • Shin Seung-Jin (Department of Otolaryngology, School of Medicine, Keimyung University) ;
  • Kim Tae-Jong (Department of Otolaryngology, School of Medicine, Keimyung University) ;
  • Nam Sung-Il (Department of Otolaryngology, School of Medicine, Keimyung University) ;
  • Ahn Byung-Hoon (Department of Otolaryngology, School of Medicine, Keimyung University)
  • 송달원 (계명대학교 의과대학 이비인후과학교실) ;
  • 손수길 (계명대학교 의과대학 이비인후과학교실) ;
  • 최종원 (계명대학교 의과대학 이비인후과학교실) ;
  • 신승진 (계명대학교 의과대학 이비인후과학교실) ;
  • 김태종 (계명대학교 의과대학 이비인후과학교실) ;
  • 남성일 (계명대학교 의과대학 이비인후과학교실) ;
  • 안병훈 (계명대학교 의과대학 이비인후과학교실)
  • Published : 2003.05.01
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Abstract

Background and Objectives: Fine needle aspiration (FNA) cytology is a simple, safe and relatively accurate procedure of diagnosing thyroid nodules. Although the frozen section biopsy is well known as more reliable method than FNA and has high specificity, whether it is necessary it leaves room for adverse criticism. Authors have compared preoperative FNA cytology and frozen section biopsy with permanent histologic findings and evaluated the significance of FNA cytology and frozen section biopsy. Materials and Methods: The medical records of 110 patiens who underwent FNA cytology and frozen section during thyroidectomy from September. 1997 to December. 2001 at the Department of Otolaryngology, School of Medicine, Keimyung University were analyzed retrospectively. Results: Sensitivity, specificity, accuracy of FNA was 75%, 91.4%, and 85.5% respcetively. Sensitivity, specificity and accuracy rate of frozen section biopsy were 92.5%, 100% and 97.3% respectively. Conclusion: FNA is simple, with rare complication and its diagnostic accuracy is comparatively so high that it is being used as primary test to diagnosis thyroid nodules. But frozen section is more accurate and may be helpful to suspicious FNA findings or if it beyond capacity of FNA. Therefore despite of the fact that the intra-operative frozen is more expensive and time consuming, it is very helpful to the treatment of thyroid nodules by using jointly with FNA.

Keywords

References

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