Advances in pediatric surgery
- 제9권1호
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- Pages.12-18
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- 2003
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- 2635-8778(pISSN)
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- 2635-8786(eISSN)
소아의 원발성 악성 간종양에 대한 임상적 고찰
The Clinical Analysis of Primary Malignant Hepatic Tumor in Childhood
- Lim, Ki-Yun (Division of Pediatric Surgery, Department of Surgery, Chonbuk National University Medical) ;
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Jeong, Yeon-Jun
(Division of Pediatric Surgery, Department of Surgery, Chonbuk National University Medical) ;
- Jung, Sung-Hoo (Division of Pediatric Surgery, Department of Surgery, Chonbuk National University Medical) ;
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Kim, Jae-Chun
(Division of Pediatric Surgery, Department of Surgery, Chonbuk National University Medical)
- 발행 : 2003.06.30
초록
The purpose of this study is to evaluate children who underwent hepatic resection for primary malignant hepatic tumor in the period from January 1994 to December 2001. A total of 8 patients, seven with hepatoblastoma (HB) and one with hepatocellular carcinoma (HCC), were studied. One HCC was resectable at the initial diagnosis, but five cases of unresectable HB received two cycles of transarterial chemoembolization (TACE) before operation. One patient with an unresectable HB with bone marrow metastasis was operated after one cycle of TACE and one cycle of systemic chemotherapy based on CCG-823F protocol. Another unresectable HB patient received systemic chemotherapy instead of TACE before operation. Postoperative chemotherapy was administered to all of the patients after complete surgical resection on CCG-823F protocol. All 6 patients who underwent TACE and neoadjuvant chemotherapy showed marked reduction in tumor volume and a clear outline of the lesion. Major complication was not noticed. Mean alpha-fetoprotein (