The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Chorea in Systemic Lupus Erythematosus: Evidence for Bilateral Putaminal Hypermetabolism on F-18 FDG PET

전신성 홍반성 루푸스에서 F-18 FDG PET상 기저핵 포도당대사 증가 소견을 보이는 무도병 1예

  • Seo, Wook-Jang (Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Chung, Son-Mi (Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Koh, Su-Jin (Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Lee, Chang-Keun (Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Kim, Jae-Seung (Department of Nuclear Medicine University of Ulsan College of Medicine, Asan Medical Center) ;
  • Im, Joo-Hyuk (Department of Neurology University of Ulsan College of Medicine, Asan Medical Center) ;
  • Yoo, Bin (Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Moon, Hee-Bom (Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center)
  • 서욱장 (울산대학교 의과대학 서울아산병원 내과) ;
  • 정선미 (울산대학교 의과대학 서울아산병원 내과) ;
  • 고수진 (울산대학교 의과대학 서울아산병원 내과) ;
  • 이창근 (울산대학교 의과대학 서울아산병원 내과) ;
  • 김재승 (울산대학교 의과대학 서울아산병원 핵의학과) ;
  • 임주혁 (울산대학교 의과대학 서울아산병원 신경과) ;
  • 유빈 (울산대학교 의과대학 서울아산병원 내과) ;
  • 문희범 (울산대학교 의과대학 서울아산병원 내과)
  • Published : 2003.10.30
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Abstract

Purpose: We describe a 54-year-old woman with systemic lupus erythematosus (SLE) who suddenly presented with chorea and had positive antiphospholipid antibodies. F-18 FDG PET showed abnormally increased glucose metabolism in bilateral putamen and primary motor cotex. Tc-99m ECD SPECT also showed abnormally increased regional cerebral blood flow in bilateral putamen. She was treated with corticosteroid and aspirin after which the symptoms improved. Four months later, follow up F-18 FDG PET showed improvement with resolution of hypermetabolism in bilateral putamen. This case suggests that striatal hypermetabolism is associated with chorea in SLE.

Keywords

References

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