Effect of Chlorella Diet Supplementation on Blood and Urine Cadmium Levels in Cadmium Poisoned Rats

  • Kim, Yong-Ho (Department of Biohealth Products Research Center, Inje University) ;
  • Hwang, Yoo-Kyeong (Department of Biohealth Products Research Center, Inje University) ;
  • Lee, Yong-Woo (Department of Biomedical Laboratory Science, Inje University) ;
  • Yun, Ji-Young (Department of Biomedical Laboratory Science, Inje University) ;
  • Hwang, Jung-Min (Department of Biomedical Laboratory Science, Inje University) ;
  • Yoo, Jai-Du (Department of Clinical Pathology, Masan College)
  • Published : 2003.09.01

Abstract

This study was conducted to investigate the influence of chlorella diet supplementation. Blood accumulation and urine excretion levels were measured after the Sprague-Dawley (SD) rats were fed on a chlorella diet supplementation mixed with 40 ppm of CdCl$_2$. Four groups tested for blood accumulation and urine excretion levels. All four groups fed on a basic diet with a cadmium mixture. The diet for the first group contained only basic diet and the cadmium added to the drinking water. The diet for the three other groups contained cadmium to the drinking water, and 1%, 5% and 10% of chlorella added to the basic diet. A concentration of cadmium for the first group showed a 3.2$\pm$0.4 $\mu\textrm{g}$/I blood accumulation level and 41.5$\pm$32.9 $\mu\textrm{g}$/l urinary excretion level, and the second group, which was fed on the basic diet with 1% of chlorella added and cadmium to the drinking water showed a $1.5\pm$0.6 $\mu\textrm{g}$/l blood level and only l4.l$\pm$1.6 $\mu\textrm{g}$/l urinary excretion level. The other two groups, which were fed on 5% and 10% of chlorella concentration and cadmium to the drinking water did not exhibit any notable effects greater than the group fed on 1% concentration of chlorella. The results suggest that the blood accumulation and urinary excretion of Cadmium are influenced by the chlorella diet supplementation from the concentration of 1% of the basic diet.

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