Real-time Interactive Control of Magnetic Resonance Imaging System Using High-speed Digital Signal Processors

고속 DSP를 이용한 실시간 자기공명영상시스템 제어

  • Published : 2003.09.01

Abstract

A real time interactive controller (spectrometer) for magnetic resonance imaging (MRI) system has been developed using high speed digital signal processors (DSP). The controller generates radio frequency (rf) waveforms and audio frequency gradient waveforms and controls multiple receivers for data acquisition. By employing DSPs having high computational power (e.g., TMS320C670l) real time generation of complicated gradient waveforms and interactive control of selection planes are possible, which are important features in real-time imaging of moving organs, e.g., cardiac imaging. The spectrometer was successfully implemented at a 1.5 Tesla whole body MRI system for clinical application. Performance of the spectrometer is verified by various experiments including high- speed imaging such as fast spin echo (FSE) and echo planar imaging (EPI). These high-speed imaging techniques reduce measurement time, however, usually intensify artifact if there is any systematic phase error or jitter in the synchronization between the transmitter, receiver, and gradients.

고속 디지털신호처리기를 사용한 자기공명영상 실시간 대화형 제어기(스펙트로미터)를 개발하였다. 개발린 제어기는 rf 파형과 경사자계 파형을 만들고, 신호 측정을 위한 다중 측정기를 제어한다. TMS320C6701과 간은 높은 계산 능력을 가진 디지털신호처리기를 사용함으로써 복잡한 경사자계파형의 실시간 계산 및 출력이 가능해졌다. 또한 회전 행렬을 실시간으로 계산함으로써 심장과 같이 움직임이 큰 장기의 실시간 영상에서 얻고자하는 평면을 대화식으로 조절이 가능해졌다. 개발된 스펙트로미터를 1.5 테슬라 전신자기공명 영상시스템에 성공적으로 적용하였다. 개발된 스펙트로미터를 고속스핀에코나 echo planar imaging(EPI) 등과 같은 초고속자기공명영상에 적용하여 성능을 검증하였다. 이것은 이들 초고속 자기공명영상기법들이 측정 시간을 단축해주는 대신에 스펙트로미터의 송신부와 수신부 또는 경사자계부간의 동기나 위상에 에러가 있을 경우 문제점을 크게 부각시켜 시스템의 성능 평가에 적합하기 때문이다.

Keywords

References

  1. P.C. Lauterbur, 'Image formation by induced local interactions : Examples employing NMR,' Nature, vol. 242, pp.190-191, 1973 https://doi.org/10.1038/242190a0
  2. T.C. Farrar, E.D. Becker, Pulse and Fourier transform NMR-introduction and theory and methods, Acamedic Press, 1971
  3. P. Mansfield, P.G. Morris, NMR imaging in biomedicine, Academic Press, 1982
  4. S. Ogawa, T-M Lee, A.R. Kay, D.W. Tank, 'Brain magnetic resonance imaging with contrast dependent on blood oxygenation,' Proc. Natl. Acad. Sci. (USA) vol. 87, pp.9868-9872, 1990 https://doi.org/10.1073/pnas.87.24.9868
  5. G.K. Schulthess, J. Hennig, Functional imaging:principles and methodology, pp. 261-390, 1997
  6. C.H. Meyer, B.S. Hu, D.G. Nishimura, A. Macovski, 'Fast Spiral coronary artery imaging,' Magn. Reson. Med., vol.28. pp. 202-213, 1992 https://doi.org/10.1002/mrm.1910280204
  7. D.A. Herzka, P. Kellman, A.H. Aletras, M.A. Guttman, E.R. McVeigh, 'Multishot EPI-SSFP in the heart,' Magn. Reson. Med. vol. 47, pp. 655-664, 2002 https://doi.org/10.1002/mrm.10105
  8. P. Mansfield, 'Multi-planar image formation using NMR spin echoes,' J. Phys. C, vol. 10, pp. 155-158, 1977
  9. C.B. Ahn, J.H. Kim, Z.H. Cho, 'High-speed spiral-scan echo planar NMR imaging-I,' IEEE Trans. Med. Imag., vol. 5, pp.1-6, 1986 https://doi.org/10.1109/MEMB.1986.5006296
  10. C.B. Ahn, S.Y. Lee, O. Nalcioglu, Z.H. Cho, 'An Improved nuclear magnetic resonance diffusion coefficient imaging method using an optimized pulse sequence,' Med. Phys., vol. 13, pp. 789-793, 1986 https://doi.org/10.1118/1.595850
  11. M. Mosley, K. Butts, M. Yenari, M. Marks, A.D. Crespigny, 'Clinical aspects of DWI,' NMR Biomed., vol. 8, pp.387-396, 1996 https://doi.org/10.1002/nbm.1940080712
  12. C.B. Ahn, S.Y. Lee, O. Nalcioglu, Z.H. Cho, 'The effects of random directional distributed flow in nuclear magnetic resonance imaging,' Med. Phys., vol. 14, pp. 43-48, 1987 https://doi.org/10.1118/1.596093
  13. F. Schmitt, M.K. Stehling, R. Turner, Echo-Planar Imaging: Theory, Technique and Application, Springer, 1998
  14. 고광혁, 권의석, 김치영, 김휴정, 김상묵, 안창범, 'DSP를 이용한 자기 공명 영상시스템의 경사자계 파형 발생기', 대한전기학회 논문지, pp.48-53, 2000
  15. S. Naruse, H. Watari, Ultrafast magnetic resonance imaging in medicine, Elsevier, 1999
  16. TMS320C6x User's guide, Texas Instruments, 2000
  17. PCI 9080 data book, PLX Tech, 1998
  18. J. Hennig, A. Naureth, H. Friedburg, 'RARE imaging: A fast imaging method for clinical MR,' Magn. Reson. Imag., Vol. 3, pp.823-833, 1986 https://doi.org/10.1002/mrm.1910030602