Korean Journal of Community Nutrition (대한지역사회영양학회지)

The Korean Society of Community Nutrition (대한지역사회영양학회)
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Development of Dietary Supplement for the Growth and Exercise Performance Improvement

성장과 운동수행능력 향상에 도움을 주는 식이조성물의 개발

  • Published : 2003.06.01
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Abstract

We developed a dietary supplement using natural herbs and nutrients for the growth and exercise performance improvement. It called 50-22 supplement containing distilled extracts of natural herbs to remove bitterness and the addition of Vitamin B1, B6, Ca and xylitol. We investigated on the effect of 10-22 supplementation on the maximal exercise performance, IGF-1 (insulin like growth factor-1) concentration and antioxidant activity in SD rat model. In result, JR-22 supplement group was better than control group about 10％ in exercise performance test and increased about 63％ of IGF-1 concentration in blood. In addition, the oxidative damage induced by exercise was reduced by JR-22 supplementation. Therefore, we suggested that 50-22 supplementation enhanced effectively exercise performance and IGF-1 concentration and reduced to oxidative stress in muscles. Also, we analysed biochemical factors in blood for the safety of JR-22 supplement. We known that there is no change of blood lactic acid, ammonia, inorganic phosphorous ion and creatine kinase activity. (Korean J Community Nutrition 8(3) : 349∼355, 2003)

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References

  1. Baranov AI (1982): Medicinal use of ginseng and rleated plants in the soviet Union. J Ethnopharm 5: 339-353
  2. Badinga L, Collier RJ, Thatcher WW, Wilcox CJ, Head HH, Bazer BW (1991): Ontogeny of hepatic bovine growth hormone receptors in cattle. J Anim Sci 69: 1925-1934 https://doi.org/10.2527/1991.6951925x
  3. Butterweck V, Jurgenliemk G, Nahrstedt A, Winterhoff H (2000): Fla-vonoids from Hypericum perforatum show antidepressant activity in the forced swimming test. Planta Med 66: 3-6
  4. Cascieri MA, Saperstein R, Hayes NS, Green BG, Chicchi GO, Apple-baum J, Bayne ML (1988) : Serum half-life and biological activity of murants of human insulin-like grwoth factor I which do not bind to serum binding proteins. Endocrinology 133: 378-381
  5. Cappola AR, Bandeen-Toche K, Wand GS, Volpato S, Fried LP (2001): Association of IGF-1 levels with muscle strength and mobility in older women. J Clin Endocrinol Metab 86: 4139-4146
  6. Chowen JA, Goya L, Ramos S, Busiguina S, Garcia-Segura LM, Argent J, Pascual-Leone AM (2002): Effects of early under on the brain in-sulin like growth factor-I system. J Neuroendocrinol 4(2): 163-169
  7. Daughaday WH, Rotwein P (1989): Insulin-like growth factors I and II, peptide messenger ribonucleic acid and gene structure, serum and tissue concentrations. Endocr Rev 10: 68-91 https://doi.org/10.1210/edrv-10-1-68
  8. Gottlieb C (1987): Adenosine triphosphate in human semen: A study on condition for a bioluminescence assay. Feril, Stertl 47: 992-999 https://doi.org/10.1016/S0015-0282(16)59235-8
  9. Hong SM, Seo YE, Kim HJ (2001): A study on nutritional status of preschool children in Ulsan area-I. Food habit and eating behavior. Journal of Human Ecology 3 (1): 77-92
  10. Kim Ku (1999): The effects of plasma growth hormone and insulin-like growth factor-1 according to work load. Journal of Physical Growth and Motor Development 7: 21-27
  11. Kim HK (1999): Fast food comsumption patterns of elementary school children. Journal of Human Ecology 1 (1): 55-68
  12. Kim CM (1999):重藥大事典, JungDam Publishing Co., Seoul
  13. Kim MH, Choi MD (2001): Deduction of relation to physical fitness and physique according to the elementary school children. Journal of Physical Growth and Motor Development 9 (1): 69-76
  14. Lee CY, Bazer FW, Etherton TD, Simmen FA (1991): Ontogeny of insulin-like growth factors (IGF-I and IGF-II) and IGF-binding proteins in porcine serum during fetal and postnatal development. Endocrinology 128: 2336-2344 https://doi.org/10.1210/endo-128-5-2336
  15. Le Roith D, Scavo L, Butler A (2001): What is the role of circulating IGF-1? TRENDS in Endocrinology & Metabolism 12(2): 48-52
  16. Marklund S, Marlund G (1974): Involvement of the superoxide anion radical in the antioxidation of pyrogallol and a convenient assay for superoxide dismutase. J Biochem 47: 469-474
  17. Paik IY, Kim JK, Chun YS, Oho HJ (1997): Verifying the validity of fatigue elements changes following absolute exercise intensities. Kor J Physical Edu 36: 218-223
  18. Poldidori MC, Mecoccis P, Cherubini A, Senin U (2000): Physical acti-vity and oxidative stress during hypertensive rats.Am J Hypertension 21: 154-157
  19. Park IY, Park TS, Oh SW, Woo JH, Jin HE, Park HR (2002): The effects of Eleutherococcus senticosus on human fatigue factors and oxidant-antioxidant system during maximal and submaximal exer-cise. Korea J Phys Edu 41: 305-315
  20. Rossiter HB, Cannerll ER, Jakeman PM (1996): The effects of oral creatine supplementation on the 1000-m performance of competi-tive rowers. J Sports Sci 14: 175-179 https://doi.org/10.1080/02640419608727699
  21. Singleton JR, Feldman EL (2001): IGF-1 in muscle metabolism and myotherapies. Neuribiol Dis 8 (4): 451-454
  22. Song Y,Han DS, Oh SW, Paik IY, Park T (2002): Effect of dietary sup-plement of Eleutherococcus Senticosus, taurine and carnitine on endurance exercise performance in rats. Korean J Nutr 35: 825-833
  23. Vina J, Gimeno A, Sastre J, Terada LS (2000): Mechanism offree radi-cal production in exhaustive exercise in humans and rats: role of xanthine oxidase and protection by allopurinol. IUBMB Life 49: 539-544
  24. Weltamn A, Weltarm JY, Schurrer R, Evans WS, Veldhuis JD, Rogol AD (1992): Endurance training amplifies the pulsatile release of growth hormone; effect of training intensity. J Appl Physiol 72: 2188-2196 https://doi.org/10.1152/jappl.1992.72.6.2188
  25. Yagi K (1976): A simple fluofometric assay for lipoperoxide in blood plasma. Biochem Med 15: 212-216
  26. Yi HJ, Chyun JH (1989): A study on the relationship between food habits, food preferences and personality traits of children. The Korean Home Economic Association 27 (2): 85-96