Nutritional Sciences
- 제6권2호
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- Pages.85-93
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- 2003
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- 1229-232X(pISSN)
Effects of a Butanol Fraction of Alisma canaliculatum and of Selenium on Blood Glucose Levels and Lipid Metabolism in Streptozotocin-Induced Diabetic Rats
- Kim, Myung-Wha (Department of Food and Nutrition, College of Natural Sciences, DukSung Women′s University)
- 발행 : 2003.05.01
초록
The purpose of this study was to investigate the effects of a butanol fraction of fraction of Alisma canaliculatum All. Braun et Bouche (Ac), and of selenium (Se), on plasma gllucose and lipid levee in streptozotocin (STD-induced diabetic rats. Male Sprague-Dawley rats, fed the AIN-93 recommended diet, were divided into five groups: a non-diabetic control group (no STZ treatment), and four 572-induced diabetic groups which consisted of a diabetic-control group, an Ac-treated group, an Ac-Se treated group, and a Se-treated group. Diabetes was induced in the rats by an injection of STZ into the tail vein at a dose of 45 mg/kg body weight. The butanol (BuOH) fraction of Ac was orally administered at a rate of 400 mg/kg body weight for 21 days to both the Ac and Ac-Se groups. The supplementation of selenium in the Se and Ac-Se groups was achieved by adding (freshly, every day) 2 mg of Se as Na