Biotechnology and Bioprocess Engineering:BBE

  • 제8권1호
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  • Pages.32-36
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  • 2003
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  • 1226-8372(pISSN)
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  • 1976-3816(eISSN)
한국생물공학회 (The Korean Society for Biotechnology and Bioengineering)
권호 표지

Light-susceptibility of Camptothecin Production from in Vitro Cultures of Camptotheca acuminata Decne

  • Park, Young-Goo (Dept. of Forestry, Kyungpook National University) ;
  • Park, Mee-Hee (Dept. of Forestry, Kyungpook National University) ;
  • Yang, Jae-Kyung (Division of Forest Science, Gyeongsang National University) ;
  • Chung, Young-Gwan (Division of Forest Science, Gyeongsang National University) ;
  • Park, Myung-Suk (Division of Forest Science, Gyeongsang National University, Institute of Agriculture and Life Sciences, Gyeongsang National University)
  • 발행 : 2003.01.01
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초록

Production of camptothecin ((PT) from callus cultures of Camptotheca acuminata Decne was affected by light and culture conditions. Among the culture media tested, modified B5 medium containing 3% (w/v) sucrose, 2 mg/L B,4-D, 2 times of MS medium vitamins, 500 mg/L casein hydrolysate, 250 mg/L myo-inositol, 0.05% (w/v) activated charcoal, and 0.15% (w/v) gelite was used for callus induction . The highest cell growth and CPT production were obtained in dark and green light condition, respectively. Photoperiod has no effect on cell growth and CPT production. Both cell growth and CPT production were also influenced by combination ratio of red and blue light .Cell growth and CPT production were the highest in the ratio of red and blue light,90:10.

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참고문헌

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