The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
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The effects of Far-infrared on Type II collagen induced mouse and the relative cytokine computerize programming (Emphasis on TNF-a and IL-1b)

원적외선이 관절염 흰쥐 모델에 미치는 영향과 관련 싸이토카인 예측 프로그래밍

  • Kim Jae Yoon (A physical therapy major, Graduate School of Rehabilitation Science, Daegu University) ;
  • Kim Jin-Sang (Department of Physical therapy, College of Rehabilitation Science, Daegu University) ;
  • Bae Sung Soo (Department of Physical therapy, College of Rehabilitation Science, Daegu University) ;
  • Park Rae Joon (Department of Physical therapy, College of Rehabilitation Science, Daegu University)
  • 김재윤 (대구대학교 대학원 재활과학과 물리치료) ;
  • 김진상 (대구대학교 재활과학대학 물리치료학과) ;
  • 배성수 (대구대학교 재활과학대학 물리치료학과) ;
  • 박래준 (대구대학교 재활과학대학 물리치료학과)
  • Published : 2003.03.01
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Abstract

The purpose of this study was to observe the effects of Far-infrared on mice rheumatoid arthritis induced by type II collagen. The author peformed several experimental tests which were the hematoxylin-eosin tissue stain, the hind paw thickness, and ELSIA of cytokines(TNF-$\alpha$, IL-1$\beta$). On day 14 and 21, FIR-Tx. group decreased in synovial membrane thickness more than control II group FIR-Tx group decreased in hind paw thickness more than control II group. In the ELISA test of TNF-$\alpha$ concentration, control II group significantly increased in the concentration more than normal and FIR-Tx. group on day 7, 14, and 21. In the ELISA test of IL-$\beta$ concentration, FIR-Tx. group decreased in the concentration more than control II group on day 14 and 21. With J's Linear Function Data Process Program, researchers can get the estimated the concentration or the hind paw thickness from this experiment. The estimated results would be a good guide to therapists and researchers, planning Far-infrared application on the rheumatoid arthritis. These results indicated that far-infrared irradiating appeared to reduce the concentration of TNF-$\alpha$ and IL-1$\beta$ at mouse model of autoimmune arthritis. It would be considered that Far-infrared has an effect on relieving rheumatoid arthritis.

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