Journal of The Korean Dental Society of Anesthesiology (대한치과마취과학회지)
- Volume 3 Issue 2 Serial No. 5
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- Pages.92-97
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- 2003
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- 1598-4044(pISSN)
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- 2383-7039(eISSN)
The Effects of Gabapentin on Facial Formalin Test
백서에서 Gabapentin 전신투여가 Facial Formalin Test에 미치는 영향
- Kim, Chul-Hong (Department of Anesthesia and Pain Medicine, College of Medicine, Pusan National University) ;
- Baik, Seong-Wan (Department of Anesthesia and Pain Medicine, College of Medicine, Pusan National University) ;
- Kim, Hae-Kyu (Department of Anesthesia and Pain Medicine, College of Medicine, Pusan National University) ;
- Kwon, Jae-Young (Department of Anesthesia and Pain Medicine, College of Medicine, Pusan National University) ;
- Kim, Kyoung-Hun (Department of Anesthesia and Pain Medicine, College of Medicine, Pusan National University) ;
- Choi, Sung-Hwan (Department of Anesthesia and Pain Medicine, College of Medicine, Pusan National University)
- 김철홍 (부산대학교 의과대학 마취과학교실) ;
- 백승완 (부산대학교 의과대학 마취과학교실) ;
- 김해규 (부산대학교 의과대학 마취과학교실) ;
- 권재영 (부산대학교 의과대학 마취과학교실) ;
- 김경훈 (부산대학교 의과대학 마취과학교실) ;
- 최성환 (부산대학교 의과대학 마취과학교실)
- Published : 2003.12.30
Abstract
Background: Gabapentin is a novel anti-epileptic drug, which is used in clinical practice to treat epilepsy. This drug is also used as an analgesic in pain patients. The antinociceptive effect of this drug was assessed using the formalin test in the rat. Methods: In order to investigate the effects of gabapentin on the trigeminal nerve territory, we injected 0.5% formalin into the upper lip. Adult, male, Sprague-Dawley rats received a