대한예방한의학회지 (Journal of Society of Preventive Korean Medicine)

대한예방한의학회 (Society of Preventive Korean Medicine)
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어성초 추출물의 세포독성(IX)

Cytotoxicity of Extracts from Houttuynia cordata(IX)

  • 이기남 (원광대학교 한의학전문대학원 제3의학과) ;
  • 이정호 (원광대학교 한의학전문대학원 제3의학과) ;
  • 송용선 (원광대학교 한의학전문대학원 제3의학과) ;
  • 정재열 (원광대학교 한의학전문대학원 제3의학과) ;
  • 김삼태 (원광대학교 한의학전문대학원 제3의학과) ;
  • 임진아 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 이인아 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 유형원 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 장용남 (원광대학교 한의과대학 예방의학교실) ;
  • 이택준 (원광대학교 한의과대학 예방의학교실) ;
  • 김홍기 (원광대학교 한의과대학 예방의학교실) ;
  • 천현자 (원광대학교 자연과학대학 자연과학기술학부) ;
  • 유일수 (익산대학 환경공업화학과) ;
  • 김종수 (익산대학 환경공업화학과) ;
  • 백승화 (원광대학교 한의학전문대학원 한약자원개발학과)
  • Lee, Ki-Nam (Dept. of Third Medicine, Professional Graduate School of Oriental Medicine, Won Kwang University) ;
  • Lee, Jeong-Ho (Dept. of Third Medicine, Professional Graduate School of Oriental Medicine, Won Kwang University) ;
  • Song, Yong-Sun (Dept. of Third Medicine, Professional Graduate School of Oriental Medicine, Won Kwang University) ;
  • Jeong, Jae-Yeal (Dept. of Third Medicine, Professional Graduate School of Oriental Medicine, Won Kwang University) ;
  • Kim, Sam-Tae (Dept. of Third Medicine, Professional Graduate School of Oriental Medicine, Won Kwang University) ;
  • Lim, Jin-A (Dept. of Herbal Resources, Professional Graduate School of Oriental Medicine, Won Kwang University) ;
  • Lee, In-A (Dept. of Herbal Resources, Professional Graduate School of Oriental Medicine, Won Kwang University) ;
  • Ryu, Hyeong-Won (Dept. of Herbal Resources, Professional Graduate School of Oriental Medicine, Won Kwang University) ;
  • Jang, Yong-Nam (School of Medicine and Dept. of Preventive Medicine, Won Kwang University) ;
  • Lee, Taek-Jun (School of Medicine and Dept. of Preventive Medicine, Won Kwang University) ;
  • Kim, Hong-Ki (School of Medicine and Dept. of Preventive Medicine, Won Kwang University) ;
  • Chun, Hyun-Ja (Division of Natural Science, Won Kwang University) ;
  • You, Il-Soo (Dept. of Environmental Engineering & Chemical Technology, Iksan College) ;
  • Kim, Jong-Soo (Dept. of Environmental Engineering & Chemical Technology, Iksan College) ;
  • Baek, Seung-Hwa (Dept. of Herbal Resources, Professional Graduate School of Oriental Medicine, Won Kwang University)
  • 발행 : 2003.06.29
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초록

This study was carried out to evaluate cytotoxic effects of Houttuynia cordata $T_{HUNB}$ extracts on A549(lung cancer), B16(mouse melanoma), MDA-MB231(breast cancer) and SNU-C4(colon cancer) cell lines. We have determined by 3-(4, 5-dimethylthiazol-2-Yl)-2, 5-diphenyl-2H-tetrazoliumbromide(MTT) assay. The $150{\mu}g/ml$ concentration of chloroform extract of Houttuynia cordata $T_{HUNB}$ was shown significantly antitoxic activity on MDA-MB231$(65.96{\pm}5.68%)$ and SNU-C4$(55.94{\pm}7.39%)$ cell lines.

키워드

참고문헌

  1. YakHak Hoeji v.44 no.2 Augmentation of macrophage cytotoxicity and NO production by pedunculagin Lee, D.I.;Kim, H.K.;Lee, M.W.;Choi, Y.W.;Kim, H.H.;Kim, E.J.
  2. Goodman and Gilman's the Pharmacological Basis of Therapeutics Gilman, A.D.;Goodman, L.S.;Rall, T.W.;Murad, F.
  3. YakHak Hoeji v.43 no.5 Synthesis and antitumor activity of novel Gericudranin E derivatives Pary, J.H.;Park, K.H.;Ho, H.S.;Kim, H.D.;Pyo, M.Y.
  4. Cancer Res. v.52 Differential effects of dietary linoleic acid on mouse skin-tumor promotion and mammary carcinogenesis Fischer, S.M.;Leytin, L.J.;Lee, M.L.;Locnislcar, M.;Belury, M.A.;Maldve, R.E.
  5. Cytotoxicity of Daucus carota L. on various cancer cells v.29 no.1 Han, E.J.;Roh, S.B.;Bae, S.J.
  6. J. Nutr. Growth Cancer v.4 Beta-carotene and smoking Gerster, H.
  7. Int. J. Cancer v.44 Serum concentration of beta-carotene and intake frequency of green-yellow vegetables aming healthy inhabitants in Japan Shibata, A.;Sasaki, R.;Ito, Y.;Reular, J.B.;Broudy, V.C.
  8. Kor. J. Pharmacogn. v.27 no.3 Isolation of anticancer agents from the leaves of Platycarya strobilacea S. et Z. Kim, Y.I.;Lee, S.H.;Cho, T.S.
  9. Korean J. Oriental Physiology & Pathology v.12 no.2 Screening of cytotoxicity and antimicrobial effects of extracts from Atractylodes macrocephala Koidz Choi, E.Y.;Oj, H.J.;Park, N.K.;Chun, H.J.;Ahn, J.W.;Jeon, B.H.;Han, D.S.;Lee, H.O.;Baek, S.H.
  10. Kor. J. Oriental Preventive Medical Society v.4 no.1 Studies on the cytotoxicity and antimicrobial effects of the extracts of Houttuynia cordata(IV) Lee, J.H.;Park, N.K.;Yang, E.Y.;Lee, H.O.;Han, D.M.;Baek, S.H.
  11. J. Korean Chemical Society v.47 no.2 The inhibitory effects of quercitrin from Houttuynia cordata against cadmium induced cytotoxicity(VII) Lee, J.H.;Lee, K.N.;Lee, C.W.;Chun, H.J.;You, I.S.;Lim, J.I.;Baek, S.W.
  12. Natural Product Letters v.4 Novel pyridine and 1, 4-dihydropyridine alkaloids from Houttuynia Cordata Probstle, A.;Neszmelyi, A.;Terkovich, G.;Wagner, H.;Bauer, R.
  13. J. Kor, Soc, Food Sci. Nutr. v.28 no.1 Effects of Houttuynia cordata ethanol extracts on serum lipids and antioxidant enzymes in rats fed high fat diet Chung, C.K.;Han, S.S.;Lee, S.Y.;Oh, D.H.;Choi, S.Y.;Kang, I.J.;Nam, S.M.
  14. Kor. J. Pharm. v.44 The inhibitory effects of Houttuynia cordata THUMB against cadmium induced cytotoxicity(II) Lee, J.H.;You, I.S.;Kim, J.S.;Lee, K.N.;Chung, W.Y.;Han, D.S.;Beak, S.H.
  15. J. Immunol. Methods v.65 Rapid colorimetric assays for cellular growth and survival : Application to proliferation and cytotoxicity assays Mosmann, T.
  16. Eur. J. Cancer v.27 Comparison of the sulforhodamine B protein and tetrazolium(MTT) assays for in vitro chemosensitivity testing Keepers, Y.P.;Pozao, P.E.;Peters, G.T.;Otte, J.A.;Winograd, B.;Pinedo, H.M.
  17. Planta Med. v.61 Virucidal effects of the steam distillate from Houttuynia Cordata and its components on HSV-1, influenze Virus, and HIV Kyoko Hayashi;Mioko Kamiya;Toshimitsu Hayashi
  18. Kor. J. Orien. Physiol. & Pathol. v.16 no.3 The water extract of caesalpinia sappan luduces apoptosis on Human lung cancer cell Line, A 549 Cells Mun, Y.J.;Nam, Y.J.;Lee, K.G.;Choi, D.H.;Lee, S.W.;Ahn, S.H.;Choi, M.K.;Woo, W.H.
  19. Yakhak Hoeji v.46 no.1 In Vitro modulation of proliferation and melanization of B16/F10 melanoma Cells by quecetin Chun, H.Y.;Hwang, S.G.;Kim, C.K.;Jeon, B.H.;Baek, S.H.;Woo, W.H.
  20. Natural Product Science v.6 no.3 Phenolic compounds from Orostachys japonicus having Anti-HIV-1 proteace activity Park, J.G.;Park, J.C.;Hur, J.M.;Kim, M.S.
  21. Arch Biochem. Biophys. v.411 no.1 Autoxidation of extracellular hydroquinones is a causative event for the cytotoxicity of menadione and DMNQ in A549-S cells Watanabe, N.;Forman, H.J.
  22. Biochim. Biophys. Acta. v.1591 no.1 Volatile organic compounds cytotoxicity and expression of HSP72, HSP90 and GRP78 stress proteins in cultured human cells Croute, F.;Poinsot, J.;Gaubin, Y.;Beau, B.;Simon, V.;Murat, J.C.;Soleilhavoup, J.P.
  23. Cancer Chemother Pharmacol. v.46 no.6 Ifosfamide metabolism and DNA damage in tumour and peripheral blood lymphocytes of breast cancer patients Johnstone, E.C.;Lind, M.J.;Griffin, M.J.;Boddy, A.V.
  24. Jpn. J. Pharmacol. v.79 no.3 Inhibitory effect of Cordyceps sinensis on spoontaneous liver metastasis of Lewis lung carcinoma and B16 melanoma cells in syngeneic mice Nakamura, K.;Yamaguchi, Y.;Kagota, S.;Kwon, Y.M.;Shinozuka, K.;Kunitomo, M.