Effects of Combination of Danggwibohyeol-tang Herbal-acupuncture on Anemic Rats

배합비율(配合比率)에 따른 당귀보혈탕(當歸補血湯) 약침(藥鍼)이 빈혈백서(貧血白鼠)에 미치는 영향(影響)

  • Jin Jae-Do (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University) ;
  • Kim Yun-Hong (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University) ;
  • Jung Tae-Young (Je-Han Oriental Medical Academy) ;
  • Seo Jeong-Chul (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University) ;
  • Leem Seong-Cheol (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University) ;
  • Han Sang-Won (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-san University)
  • 진재도 (경산대학교 한의과대학 침구학교실) ;
  • 김윤홍 (경산대학교 한의과대학 침구학교실) ;
  • 정태영 (제한동의학술원) ;
  • 서정철 (경산대학교 한의과대학 침구학교실) ;
  • 임성철 (경산대학교 한의과대학 침구학교실) ;
  • 한상원 (경산대학교 한의과대학 침구학교실)
  • Published : 2003.06.27

Abstract

Objective; This study was investigated to test the anti-anemic effects of Danggwibohyeol-tang for herbal acupuncture on rat with anemia induced by phenylhydrazine according to composition ratio. Methods; Danggwibohyeol-tang herbal-acupuncture was administered into Kyoksu(膈兪穴, BL17) and RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, platelet, MPV, PDW, indirect bilirubin and lactate dehydrogenase were tested. Results; The obtained results are summarized as follows: (1) In control group RBC was significantly reduced in comparison with normal group. And in Danggwibohyeol-tang group A, B, C there was significant inhibitory effect on reduction in comparison with control group. The effect of Danggwibohyeol-tang group C was similiar to that of Danggwibohyeol-tang group B and was higher than that of Danggwibohyeol-tang group A. (2) In control group hemoglobin was significantly reduced in comparison with normal group. And in Danggwibohyeol-tang group A, B, C there was significant inhibitory effect on reduction in comparison with control group but there was no significant difference between Danggwibohyeol-tang group A, B, C. (3) In control group hematocrit was significantly reduced in comparison with normal group. And in Danggwibohyeol-tang group A, B, C there was significant inhibitory effect on reduction in comparison with control group. The effect of Danggwibohyeol-tang group C was higher than that of Danggwibohyeol-tang group A or B. (4) In case of MCV, MCH, MCHC and RDW there was no significant anti-anemic effect. (5) Danggwibohyeol-tang group significantly inhibited the growth of platelet. In case of Danggwibohyeol-tang A and B group there was more inhibitory effect than Danggwibohyeol-tang C group but there was no significant difference between Danggwibohyeol-tang A and B group. (6) In case of MPV, PDW and indirect bilirubin there was no significant difference between Danggwibohyeol-tang group and control group. (7) Danggwibohyeol-tang group significantly inhibited the growth of lactate dehydrogenase. In case of Danggwibohyeol-tang C group there was more inhibitory effect than Danggwibohyeol-tang B group and Danggwibohyeol-tang B group showed more inhibitory effect than Danggwibohyeol-tang A group. Conclusion; From above results Danggwibohyeol-tang for herbal acupuncture showed significant anti-anemic effect in some parameters. Further study is needed for the effect of Danggwibohyeol-tang according to different composition ratio.

Keywords

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