Journal of Pharmacopuncture (대한약침학회지)

KOREAN PHARMACOPUNCTURE INSTITUTE (대한약침학회)
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The Experimental Study on Chaenomelis Fructus(木瓜) in Case of the Arthritis Induced by Injecting Freund's Complete Adjuvant

목과(木瓜)의 Adjuvant 관절염(關節炎)에 대한 실험적(實驗的) 연구(硏究)

  • Kwon, Kang (Department of Acupuncture & Moxibustion, College of Oriental Medical, Sangji University) ;
  • Park, Ki-Chul (Department of Acupuncture & Moxibustion, College of Oriental Medical, Sangji University) ;
  • Sohn, Seong-Hyun (Department of Acupuncture & Moxibustion, College of Oriental Medical, Sangji University) ;
  • Park, Hee-Soo (Department of Acupuncture & Moxibustion, College of Oriental Medical, Sangji University)
  • 권강 (상지대학교 한의과대학 침구학교실) ;
  • 박기철 (상지대학교 한의과대학 침구학교실) ;
  • 손승현 (상지대학교 한의과대학 침구학교실) ;
  • 박희수 (상지대학교 한의과대학 침구학교실)
  • Published : 2003.06.30
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Abstract

9Objective : We carried out this experimental study in order to investigate the effect of Chaenomelis Fructus(木瓜) extract and herbal-acupuncture on the arthritis induced by injecting Freund's complete adjuvant Method : 1. We categorized SD-rats into five groups as followings. (1) Control: Without any Treat (2) Treat I: treated by acupuncture (3) Treat II: treated by drinking 5% saline (4) Treat III: treated by drinking Chaenomelis Fructus(木瓜) extract (5) Treat IV: treated by Chaenomelis Fructus(木瓜) herbal-acupuncture 2. We established ten items for decision of experimental results as followings Edema rate, Pain endurance, WBC, Hemoglobin, Platelet, Total protein, Albumin, Globulin, RA factor, CRP Results : The groups that showed significant effects compared with Contol group were explained as followings. 1. Edema rate : Treat I , Treat III 2. Pain endurance : Treat I, Treat IV 3. WBC : Treat IV 4. Hemoglobin : Treat III 5. Plat99elet : Treat IV 6. Total protein : Treat I, Treat IV 7. Albumin : None 8. Globulin : Treat I, Treat IV 9. RA factor : Treat I, Treat IV 10. CRP : Treat IV Conclusion : Observing above experimental results, we can guess that the effects of acupuncture and Chaenomelis Fructus(木瓜) herbal-acupuncture on Freund's adjuvant arthritis are more superior than other ways. In addition, we can find that the latter is more better than the former in effect by two items(platelet, CRP).

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References

  1. 黃帝內經 章句索引 任應秋
  2. 針灸學 全國韓醫科大學 針灸經穴學敎室(編)
  3. Arch Int Pharmacodyn. v.188 A method for measurement of analgesic acrivity on inflammed tissue Randall, L.D.;Sellitto, J.J.
  4. 大韓藥鉞學會誌 v.1 no.1 藥物注入의 技法的 始源에 대한 小考 안상우 https://doi.org/10.3831/KPI.1997.1.1.087
  5. 實用中醫內科學 黃文東(外)
  6. 東醫 再活醫學科學 全國韓醫科大學 再活醫學科學敎室(編)
  7. 本草學 全國韓醫科大學 本草學敎授(編)
  8. Drug Exp. Clin. Res. v.17 no.10;11 Immunosupressive activity of 15-deoxyspergualin (15-DOS) on various models of rheumatoid arthritis Schorlemmer, H.U.;Bartlett, R.R.;Schleyerbach, R.;Seiler, F.R.
  9. 慶熙韓醫大論文集 v.13 穴位別 草鳥水針刺戟이 흰쥐의 Adjuvant 關節炎에 미치는 影響 康秀一;崔容泰
  10. 東國大學校 碩士學位論文 v.8 濃度別 紅花水鉞이 흰쥐의 Adjuvant誘發關節炎에 미치는 影響 兪元根
  11. 東醫病理學會誌 v.8 蜂毒이 흰쥐의 Adjuvant關節炎에 미치는 影響 朴亨奎;河智容;安圭錫
  12. 大韓針灸學會誌 v.17 赤芍藥藥針이 rat의 Adjuvant關節炎에 미치는 影響 孫承鉉;朴喜守
  13. 大韓韓醫學會誌 v.10 no.1 鉞灸 및 泰水鉞이 흰쥐의 Adjuvant關節炎에 미치는 影響 金正坤;李潤浩;朴東錫
  14. Immunobiology v.190 no.1;2 Time course of antibodies against IgG and type II collagen in adjuvant arthritis. Role of mycobacteria administration in antibody production French, A.;Cassany, S.;Castellote, C.;Castell, M. https://doi.org/10.1016/S0171-2985(11)80285-8
  15. 慶熙大學校 博士學位論文集 v.10 草龍膽水針에 의한 肝機能改善이 關節炎症性 浮腫에 미치는 影響 金甲成
  16. 針灸學 上海中醫學院
  17. Ann. Rheum. dis. v.29 Lysosomal enzyme activity in rats with adjuvant induced arthritis Anderson, A.J. https://doi.org/10.1136/ard.29.3.307
  18. Parmacol Exptl v.141 Anti-inflammatory and Antipyretic Activities of Indomethacin, 1-p-(chlopobenzoyl)-5-Methyl-Indole-3-Acetic Acid Winter, C.A.;Risley, E.A.;Nuss, G.W.
  19. Arch int pharmacodyn. Acomparative study of the Lewis and Spra-gue Dawley rat in adjuvant arthritis Rosenthale, M.E.
  20. 整形外科學 大韓整形外科學會(編)
  21. 成人病 ${\cdot}$ 老人病學 徐舜圭
  22. Textbook of Medicine Cohen, Alan S.
  23. 그림으로 설명한 병리학 이중달(編)
  24. 備急千金要方 孫思邈
  25. 醫學入門(雜病編) 李정
  26. 萬病回春 공廷賢
  27. 景岳全書 張介賓
  28. 醫學心悟 程國彭
  29. 金궤要略注釋 張仲景
  30. 韓方病理學 全國 韓醫科大學 病理學敎室(編)
  31. 臨床病理檢査法 이삼열
  32. 臨床化學實技 김종호(외)
  33. 大韓東醫病理學會誌 v.12 no.2 刺針이 류마치스性 關節炎에 미치는 效果 朴慶寔
  34. J. Tradit Chin Med v.13 no.3 Effect of acupuncture and point-injection Treat on immunologic function in rheumatoid arthritis 劉心蓮;孫雨金;肖君
  35. 大韓針灸學會誌 v.16 no.1 흰쥐의 關節炎에 미치는 熊膽 ${\cdot}$牛黃藥針과 猪膽 ${\cdot}$ 牛黃藥針의 效能硏究 나창수(外)
  36. 梔子藥針이 白鼠의 adjuvant關節炎에 미치는 影響 김낙현
  37. 大韓針灸學會誌 v.16 no.3 牛膝 및 峰毒藥針이 생쥐의 LPS 誘發關節炎의 細胞性 免疫反應에 미치는 影響 李昇德;金甲成
  38. Res. Exp. Med. v.197 Methotrexate suppresses nitri oxide prouction ex vivo in macrophages from rats with adjuvant-induced arthritis Schoromata, T.;Segawa, Y.;Inoue, N.;Tsuzuike, N.;Itokazu, Y.;Tamaki, H. https://doi.org/10.1007/s004330050057
  39. 物理療法學會誌 v.5 no.1 骨膽草가 제II형 Collagen 誘發 關節炎이 抗體에 미치는 影響 嚴載元(外4人)
  40. 東醫物理療法科學會誌 v.4 大羌活湯이 제II형 Collagen 誘發 關節炎의 抗體에 미치는 影響 李昊根(外2人)
  41. 經絡 I 南相千
  42. 奇蹟의 藥針要法I ${\cdot}$II및 製劑法 金廷彦
  43. J Pheumatol v.21 no.3 Experimental induction of arthritis in rats immunized with Escherichia coli 0:14 lipopoly-saccharide Noyori, K.;Okamoto, R.;Takagi, T.;Hyodo, A.;Suzuki, K.;Koshino, T.
  44. 藥針에 대한 紹介 및 臨杉報告書 황재옥
  45. 經穴學叢書 安榮基(編)
  46. 韓藥臨床應用 李尙仁(外)
  47. 大韓針灸學會誌 v.15 no.1 類風濕性關節炎 中醫藥治 療與硏究進展槪況 袁寶權
  48. 임상병리파일 이귀녕;이종순
  49. 臨床血液學 邊大勳
  50. 臨四病理學 大韓臨床病理學會
  51. 內科學(下) 李文鎬(外)
  52. 臨床化學實技 서덕규(外)
  53. 神藥 金一勳