Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
권호 표지

EPITHELIAL-MYOEPITHELIAL CARCINOMA OF THE PAROTID GLAND : A CASE REPORT

이하선에 발생한 상피근상피암

  • You, Tae-Min (Department of Oral & Maxillofacial Surgery, School of Dentistry, Yonsei University) ;
  • Jung, Young-Soo (Department of Oral & Maxillofacial Surgery, School of Dentistry, Yonsei University) ;
  • Kim, Moon-Key (Department of Oral & Maxillofacial Surgery, School of Dentistry, Yonsei University) ;
  • Cha, In-Ho (Department of Oral & Maxillofacial Surgery, School of Dentistry, Yonsei University) ;
  • Kim, Jin (Department of Oral Pathology, School of Dentistry, Yonsei University) ;
  • Kim, Hyung-Jun (Department of Oral & Maxillofacial Surgery, School of Dentistry, Yonsei University)
  • 유태민 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 정영수 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 김문기 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 차인호 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 김진 (연세대학교 치과대학 구강병리학교실) ;
  • 김형준 (연세대학교 치과대학 구강악안면외과학교실)
  • Published : 2003.04.30
Download PDF
⟨ Previous Next ⟩

Abstract

Epithelial-myoepithelial carcinoma(EMC) of the salivary glands is a rare tumor first discribed in 1972. The EMC comprises approximately 1% of all salivary gland tumors. It is characterized by tubular and solid growth pattern with a dual cell population including an inner layer of epithelial cells, which is peripherally bounded by a layer of clear myoepithelial cells. It is demonstrated that tumor with solid slowly growing pattern, generally have a higher frequency of local recurrence. We report a case of parotidic EMC in a 30 years old woman with literature review

상피근상피암은 타액선, 특히 이하선에 호발하는 매우 드문 악성 종양으로 내측의 상피세포와 외측의 투명한 근상피세포의 2열구조로 구성되어 있는 것이 특징이고. 비교적 국소 재발 및 전이를 잘하는 것으로 보고 되었다. 저자들은 드문 타액선 종양인 상피근 상피암을 이하선에서 경험하였기에 문헌 고찰과 함께 보고하였으며, 본 증례의 경우 향후 재발 및 전이 여부 파악 위해 주기적인 경과 관찰이 필요하리라 사료된다.

Keywords

References

  1. Seifert G, Sobin LH : Histological typing of salivary gland tumours. In: World Health Organization International Histological Classification of Tumors. 2nd edn. Berlin: Springer-Verlag 1991.
  2. Batsakis JG, El-Naggar AK, Luna MA : Epithelial-myoepithelial carcinoma of salivary glands. Ann Otol Rhinol Laryngo 101: 540-542, 1992. https://doi.org/10.1177/000348949210100617
  3. Simpson RHW, Clarke TJ, Sarsfield PTL et al : Epithelial-myoepithelial carcinoma of salivary glands. J Clin Pathol 44: 419-423. 1991.
  4. Cho KJ, El-Naggar AK, Ordonez NG et al : Epithelial-myoepithelial carcinoma of salivary glands. A clinicopathologic, DNA flow cytometric and immunohistochemical study of Ki-67 and HER-2/neu oncogene. Am J Clin Pathol 103: 432-437, 1995. https://doi.org/10.1093/ajcp/103.4.432
  5. Fonseca I, Soares J. : Epithelial-myoepithelial carcinoma of the salivary glands. A study of 22 cases. Virchow Archiv A pathol Anat 422: 389-396, 1993.
  6. Seifert G, Brocheriou C, Cardesa A et al : WHO international classification of tumors. Tentative histological classification of salvary gland tumors. Pathol Res. Pract. 186: 555-581, 1990.
  7. Marrow TA, Chun T, Mirani N : Epithelial-myoepithelial carcinoma of salivary glands. Ear Nose Throat 69: 646-648, 1990.
  8. Moringana S, Hashimoto S, Tezuka F : Epithelial-myoepithelial carcinoma of the parotid gland in a child. Acta Pathol Jpn 42: 358-363, 1992.
  9. Nistal M, Garcia-Viera M, Martinez-Garcia C et al : Epithelialmyoepithelial tumor of the bronchus. Am J surg Pathol 18; 421-5, 1994.
  10. Wick MR, Ockner DM, Mills SE et al : Homologous Carcinomas of the Breasts, Skin and Salivary Glands. Am J Clin Pathol 109: 75-84, 1998. https://doi.org/10.1093/ajcp/109.1.75
  11. Corio RL, Sciubba JJ, Branon RB et al : Epithelial-myoepithelial carcinoma of intercalcated duct origin. A clinicopahologic and ultrastructural assesment of sixteen cases. Oral Surg Oral Med Oral Pathol 53: 280-7, 1982. https://doi.org/10.1016/0030-4220(82)90304-8
  12. Tralongo V, Daniele E : Epithelial-myoepithelial carcinoma of salivary glands: A review of literature. Anticancer Res 18: 603-8, 1998.
  13. H.Deere, M.B.B.S, I. Hore, F.R.C.S, N. Mcdermott et al : Epithelialmyoepithelial carcinoma of the parotid gland: a case report and review of the cytological and histological features. J of Larygology & Otology. 115: 434-436, 2001.
  14. Hans-Udo Kasper, Walter Mellin et al : Epithelial-myoepithelial Carcinoma of the Salivary Gland-A Low Grade Malignant Neoplasm? Report of Two Cases and Review of the Literature. Pathol. Res. Pract. 195: 189-192, 1999.
  15. Donath K, Seifert G, Schmitz R : Diagnosis and ultrastructure of the tubular carcinoma of salivary gland ducts. Epithelial-myoepithelial carcinoma of the intercalated ducts. Virchows Arch(Pathol Anat) 356: 16-31, 1972. https://doi.org/10.1007/BF00543554
  16. Noel S, Bronza JP: Epithelial -myoepithelial carcinoma of salivary gland with metastasis to lung : report of a case and review of the literature. Head and neck 14: 401-406, 1992. https://doi.org/10.1002/hed.2880140512
  17. Toida M, Shimokawa K : Epithelial myoepithelial carcinoma of the parotid gland: report of a case. J oral Maxillfac Surg 53: 476-80, 1995
  18. 강기훈,김장묵,송태현 등 : 이하선 상피-근상피암종 1예, 대한식도외과학회지, 6(1) : 108-112, 2000.