Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • 제29권2호
  • /
  • Pages.79-85
  • /
  • 2003
  • /
  • 2234-7550(pISSN)
  • /
  • 2234-5930(eISSN)
대한구강악안면외과학회 (The Korean Association of Oral and Maxillofacial Surgeons)
권호 표지

가토에서 하악골 신연 6주후 신연양에 따른 두개하악관절의 조직병리학적 변화

HISTOPATHOLOGIC CHANGES OF THE CRANIOMANDIBULAR JOINT ACCORDING TO THE AMOUNT OF DISTRACTION AFTER 6 WEEKS OF DISTRACTION OSTEOGENESIS IN RABBITS

  • 김현호 (조선대학교 치과대학 구강생물학연구소) ;
  • 김수관 (조선대학교 치과대학 구강생물학연구소) ;
  • 임성철 (조선대학교 의과대학 병리학교실) ;
  • 정해만 (조선대학교 치과대학 구강악안면외과, 인체생물학교실) ;
  • 김생곤 (조선대학교 치과대학 구강악안면외과, 인체생물학교실)
  • Kim, Hyun-Ho (Oral Biology Research Institute, College of Dentistry, Medical Research Institute, College of Medicine, Chosun University) ;
  • Kim, Su-Gwan (Oral Biology Research Institute, College of Dentistry, Medical Research Institute, College of Medicine, Chosun University) ;
  • Lim, Sung-Chul (Department of Pathology, Medical Research Institute, College of Medicine, Chosun University) ;
  • Chung, Hae-Man (Dept. of Oral & Maxillofacial Surgery, Dept. of Human Biology, Medical Research Institute, College of Medicine, Chosun University) ;
  • Kim, Sang-Gon (Dept. of Oral & Maxillofacial Surgery, Dept. of Human Biology, Medical Research Institute, College of Medicine, Chosun University)
  • 발행 : 2003.04.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

The purpose of this study is to observe histopathologic changes in the bilateral craniomandibular joints after allowing 6 weeks of consolidation by varying the amount of distraction in rabbit mandible. Eight rabbits weighing about 2 to 3 kg were used. After corticotomy was performed on the left mandibular body between the first premolar and the second premolar region, a unilateral fixation device was placed. Then, a 7-day period was allowed without distraction of the device. The mandible was lengthened 0.5 mm/day. Corticotomy and lengthening of mandible were not performed in control group. After the completion of the lengthening process, a 6-week-consolidation period was allowed. Then, the rabbits were sacrificed, and histologic examination of the craniomandibular joints was performed. Proliferative changes were observed in the craniomandibular joints in all groups. With the increasing amount of distraction, hypertrophy of the cartilage layer became more severe, bone formed was dense and enchondral ossification was clearly shown in subchondral bone. Hypertrophy of the cartilage layer was also seen in the non-distracted side as the distracted side in the experimental group. These results indicate that when physical force is applied constantly to joints, the proliferation of articular cartilage and bone formation are present. When more than 6 weeks of consolidation period is allowed at the time of performing distraction for more than 5 mm, articular changes, especially, in the contralateral side should also be noted.

키워드

참고문헌

  1. 김기영, 유선열 : 가토에서 하악골 신연 양에 따른 하치조신경의 조직학적 변화. 대한악안면성형재건외과학회지 1998;20:250-255
  2. 김수관, 김소영, 권병곤 : 골신전술을 이용한 하악 치조골 증대술. 대한악안면성형재건외과학회지 2002;24:158-164
  3. McCarthy JG : Distraction of the craniofacial skeleton. New York, Springer, pp 1999; 249-271
  4. Komuro Y, Takato T, Harii K, Yonemara Y : The histologic analysis of distraction osteogenesis of the mandible in rabbits. Plast Reconstr Surg 1994;94:152-159 https://doi.org/10.1097/00006534-199407000-00017
  5. Ilizarov GA : A new principle of osteosynthesis with the use of crossing pins and rings. In Collection of Scientific Works of the Kurgan Regional Scientific Medical Society. Kurgan, USSR, 1954; 145-160
  6. Ilizarov GA : Basic principles of transosseous compression and distraction osteosynthesis. Ortop Travmatol Protez 1971;32:7-15
  7. Ilizarov GA : The tension-stress effect on the genesis and growth of tissues : Part I. The influence of stability of fixation and soft-tissue preservation. Clin Orthop 1989;238:249-281
  8. Ilizarov GA : The tension-stress effect on the genesis and growth of tissues : Part II. The influence of the rate and frequency of distraction. Clin Orthop 1989;239:263-285
  9. Fisher E, Staffenberg DA, McCarthy JG, Miller DC, Zeng J : Histopathologic and biochemical changes in the muscles affected by distraction osteogenesis of the mandible. Plast Reconstr Surg 1997;99:366-371 https://doi.org/10.1097/00006534-199702000-00009
  10. Aronson J, Good B, Stewart C, Harrison B, Harp J : Preliminary studies of mineralization during distraction osteogenesis. Clin Orthop 1990;250:43-49
  11. Windhager R, Tsuboyama T, Siegl H, Groszschmidt K, Seidl G, Schneider B, Plenk H Jr : Effect of bone cylinder length on distraction osteogenesis in the rabbit tibia. J Orthop Res 1995;13:620-628 https://doi.org/10.1002/jor.1100130419
  12. Frierson M, Ibrahim K, Boles M, Bote H, Ganey T : Distraction osteogenesis. A comparison of corticotomy techniques. Clin Orthop 1994;301:19-24
  13. Karp NS, Thorne CH, McCarthy JG, Sissons HA : Bone lengthening in the craniofacial skeleton. Ann Plast Surg 1990;24:231-237 https://doi.org/10.1097/00000637-199003000-00007
  14. 정훈, 오아유다, 허원실 : 악관절의 생화학적 검토. 대한치과의사협회지 1996;34:315-318
  15. Weinberg S, Craft J : Unilateral atrophy of the mandibular condyle after closed subcondylar osteotomy for correction of mandibular prognathism. J Oral Surg 1980;38:366-368
  16. Bouvier M, Zimmy ML : Effects of mechanical loads on surface morphology of the condylar cartilage of the mandibule in rats. Acta Anat 1987;129:293-300 https://doi.org/10.1159/000146418
  17. Nakamura E, Mizuta H, Sei A, Takagi K : Knee articular cartilage injury in leg lengthening. Histological studies in rabbits. Acta Orthop Scand 1993;63:437-440
  18. Harper RP, Bell WH, Hinton RJ, Browne R, Cherkashin AM, Samchukov ML : Reactive changes in the temporomandibular joint after mandibular midline osteodistraction. Br J Oral Maxillofac Surg 1997;35:20-25 https://doi.org/10.1016/S0266-4356(97)90004-8
  19. Karaharju-Suvanto T, Peltonen J, Laitinen O, Kahri A : The effect of gradual distraction of the mandible on the sheep temporomandibular joint. Int J Oral Maxillofac Surg 1996;25:152-156 https://doi.org/10.1016/S0901-5027(96)80063-4