Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Hypoglycemic Effect of Polysaccharide Isolated from Eclipta alba L.

한련초로부터 정제한 다당체의 혈당강하 효과

  • 우은란 (조선대학교 약학대학 약학과) ;
  • 이동행 (조선대학교 약학대학 약학과) ;
  • 문영희 (조선대학교 약학대학 약학과)
  • Published : 2003.09.30
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Abstract

The major polysaccharide, named EAP, was purified from the aerial parts of Eclipta alba by Sepharose CL-2B ion exchange chromatography and recycling HPLC. The molecular weight of EAP was estimated to be 20911.9 D by MALDI-TOF MS. In addition, the sugar composition was determined to be arabinose (23.6%), mannose (24.8%), galactose (12.3%), and glucose (41.3%), respectively, by GC analysis. The EAP decreased the blood sugar level, which was induced by alloxan in rats, dose dependently.

Keywords

References

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