Natural Product Sciences

  • 제9권4호
  • /
  • Pages.232-234
  • /
  • 2003
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  • 1226-3907(pISSN)
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  • 2288-9027(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

A New Glycerol Ether from a Marine Sponge Stelletta Species

  • 발행 : 2003.12.01
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초록

A new glycerol ether has been isolated from a marine sponge Stelletta sp. By bioactivity-guided fractionation. The structure was established on the basis of NMR and MS analyses. The compound was evaluated for cytotoxicity against a small panel of five human tumor cell lines and exhibited significant cytotoxicity.

키워드

참고문헌

  1. Barbara, L. and Phillp, C. Chiral ether glycerides from a marine sponge. J. Org. Chem., 48, 3585-3587 (1983) https://doi.org/10.1021/jo00168a052
  2. Bergquist, P.,Lawson, M. P.,Lavis, A and Cambie, R. C. Fatty acid composition and the classification of the Porifera. Biochem. Syst. Ecol., 12, 63-84 (1984) https://doi.org/10.1016/0305-1978(84)90012-7
  3. Costantino, V., Fattorusso, E., Mangoni, A, Aknin, M., Fall, A, Samb, A and Miralls, J. An unusual ether glycolipid from the Senegalese sponge Trikentrion loeve carter. Tetrahedron, 49, 2711-2716 (1993) https://doi.org/10.1016/S0040-4020(01)86348-1
  4. Guerriero, A, Debitus, C. and Pietra, E On the first marine stigmastane sterols and sterones having a 24,25-double bond. Isolation from the sponge Stelletta sp. of deep coral sea. Helv. Chim. Acta, 74, 487-494 (1991) https://doi.org/10.1002/hlca.19910740304
  5. Li, H., Matsunaga, S. and Fusetani, N. Bioactive marine metabolites. 62. A new 9,11-secosterol, stellettasterol from a marine sponge Stelletta sp. Experientia, 50, 771-773 (1994) https://doi.org/10.1007/BF01919380
  6. Liu, Y, Lee, C. O., Hong, J. and Jung, J. H. Cyclitol derivatives from the sponge Sarcotragus species. Bull. Korean Chem. Soc., 23, 1467-1469 (2002) https://doi.org/10.5012/bkcs.2002.23.10.1467
  7. Matsunaga, S., Yamashita, T., Tsukamoto, S. and Fusetani, N. Three new antibacterial alkaloids from a marine sponge Stelletta sp. J. Nat. Prod., 62, 1202-1204 (1999) https://doi.org/10.1021/np990161k
  8. McCormick, J. L., McKee, T. C, Cardellina, J. H., Leid, M. and Boyd, M. R. Cytotoxic triterpenes from a marine sponge Stelletta sp. J. Nat. Prod., 59, 1047-1050 (1996) https://doi.org/10.1021/np960541v
  9. Meyer, B. N., Ferrigni, N. R., Putnam, J. E., Jacobsen, L. B., Nichols, D. E. and McLaughlin, J. L. Brine shrimp: A convenient general bioassay for active plant constituents. Planta Med., 45, 31-34 (1982) https://doi.org/10.1055/s-2007-971236
  10. Nazawa, D., Takikawa, H. and Mori, K. Synthesis and absolute configuration of stellettadine A: A marine alkaloid that induces larval metamorphosis in Ascidians. Bioorg. Med. Chem. Lett., 11, 1481-1483 (2001) https://doi.org/10.1016/S0960-894X(01)00015-4
  11. Oku, N., Matsunaga, S., Wada, S. I., Watabe, S. and Fusetani, N. New isomalabaricane triterpenes from the marine sponge Stelletta globostellata that induce morphological changes in rat fibroblasts. J. Nat. Prod., 63, 205-209 (2000) https://doi.org/10.1021/np990333d
  12. Quijano, L., Cruz, F, Navarrete, I., Gomez, P. and Rios, T. Alkyl glycerol monoethers in the marine sponge Desmapsarnma anchorata. Lipids, 29, 731-734 (1994) https://doi.org/10.1007/BF02538919
  13. Ryu, G., Matsunaga, S., Fusetani, N. Globostellatic acids A-D, new cytotoxic isomalabaricane triterpenes from the marine sponge Stelletta globostellata. J. Nat. Prod., 59, 512-514 (1996) https://doi.org/10.1021/np9601317
  14. Tsukamoto, S., Yamashita, T., Matsunaga, S. and Fusetani, N. Bistellettadines A and B: Two bioactive dimeric stellettadines from a marine sponge Stelletta sp. J. Org. Chem.,64, 3794-3795 (1999) https://doi.org/10.1021/jo9903252
  15. Yan, S. J., Su, J. Y, Zhang, G. W., Wang, Y. H. and Li, H. Ketosterols from Stelletta tenuis. Zhongshan Daxue Xuebao, 40, 54-57 (2001)
  16. Zhao, Q., Lee, S. Y, Hong, J., Lee, C. O., Im, K. S., Sim, C. J., Lee, D. S. and Jung, J. H. New acetylenic acids from a marine sponge Stelletta species. J. Nat. Prod., 66, 408-411 (2003a) https://doi.org/10.1021/np020440z
  17. Zhao, Q., Mansoor, T. A, Hong, J., Lee, C. O., Im, K. S., Sim, C. J., Lee, D. S. and Jung, J. H. New cytotoxic lysophosphatidylcholines and monoglycerides from a marine sponge Stelletta species. J. Nat. Prod., 66, 725-728 (2003b) https://doi.org/10.1021/np0300075
  18. Zhao, Q., Liu, Y, Hong, J., Lee, C. O., Park, J. H., Lee, D. S. and Jung, J. H. A new cyclitol derivative from a sponge Stelletta species. Nat. Prod. Sci., 9, 18-21 (2oo3c)