Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Evaluation of Antidiarrhoeal Activity of Aerva species

  • Joanofarc, J. (Department of Pharmacognosy, Vels College of Pharmacy) ;
  • Vamsadhara, C. (Institute of Pharmacology, Madras Medical College)
  • Published : 2003.09.01
Download PDF
⟨ Previous Next ⟩

Abstract

The genus Aerva is distributed is temperate and stropical Asia and Africa. Aerva species, Aerva lanata and Aerva javanica have been used for antidiarrhoeal activity in Indian traditional medicine. A.lanata and A.javanica were screened separately for their. anti-diarrhoeal activity and their action on intestinal transit on their vacuum dried ethanolic and aqueous extracts at the dose of 800 mg/kg by standard methods. All the extracts showed significant antidairrhoeal activity and significantly reduced intestinal transit in charcoal meal test. The results illustrate that the ethanolic and aqueous extracts of A.lanata and the ethanolic and aqueous extracts of A.javanica have significant antidiarrhoeal activity and the activity may be attributed to its effect on intestinal transit. The present study supports the claim of Aerva lanata and Aerva javanica as antidiarrhoeal drugs in the Indian system of medicine.

Keywords

References

  1. Anonymous., The Wealth of India, Vol-l , CSIR Publications, New Delhi, India, pp. 92 (1985)
  2. Anonymous., Pharmacognosy of Ayurvedic Drugs, Published by Pharmacognosy Unit, Kerala, India, pp. 25-26 (1994)
  3. Awouters, F., Niernegeers, C. J. E., Lenaerts, E M. and Janssen, P. A J., J. Pharm. Pharmacol., 30, 41 (1978) https://doi.org/10.1111/j.2042-7158.1978.tb13150.x
  4. Geissman, T. A., Modern Methods of Plant Analysis, Springer Verlag, New York, pp. 163 (1995)
  5. Goodman and Gilrnan., The Pharmacological Basis ofTherapeutics, 9, pp. 543 and 924 (1996)
  6. Jain, S. K, Dictionary ofIndian Folk Medicine and Ethnobotany, Deep publications, pp. 15 (1991)
  7. Mujumdar, A M., Anti diarrhoeal activity of Azadirachta indica leaf extract, Indian Drugs, 35(7), 417-420 (1998)
  8. Perry, M., Medicinal plants East and South East Asia, Attributed properties and uses, The MIT press, Cambridge, pp. 9 (1980)
  9. Sunil Bajad.,K. L. Bedi., A.K Singla, and R.K Johri., Antidiarrhoeal activity of piperine in mice, Planta Med, 67, 284-286 (2001) https://doi.org/10.1055/s-2001-11999
  10. Tripathi, K. D., Essentials ofMedical Pharmacology, Jaypee Brothers Medical Publishers, New Delhi, India, pp. 657 (2001)
  11. Yoganarasimhan, S. N., Medicinal plants of India, Tamil Nadu, Vol 2, pp. 24-25 (2000)
  12. Zaval, M. A, Pera, Z. S., Perez, P., Vargan, R., and Perez, R. M., Anti diarrhoealactivity of Waltheria anorlana, Commelina coelestis and Altemanthera repens, Journal of Ethnopharmacology, 61, 41-47 (1988)