Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Hypoglycemic, Antidiabetic and Antiulcer Screening of Thespesia Populnea Linn

  • Jayakumari, S. (Department of Pharmacognosy, Vels College of Pharmacy) ;
  • Rajkumar, M. (Department of Pharmacognosy, Vels College of Pharmacy) ;
  • Joanofarc, J. (Department of Pharmacognosy, Vels College of Pharmacy) ;
  • Rao, G. Srinivasa (Department of Pharmacognosy, Vels College of Pharmacy) ;
  • Kumar, S. Sadish (Department of Pharmaceutical Chemistry, Vels College of Pharmacy) ;
  • Umadevi, S.K. (Department of Pharmaceutics, Vels College of Pharmacy)
  • Published : 2003.09.01
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Abstract

In the present study, Thespesia populnea was extracted with alcohol and water. The extracts were vacuum dried to yield the respective alcoholic and aqueous extracts. The extracts were screened for hypoglycemic, antidiabetic and antiulcer activities at the dose level of 500 mg/kg by standard methods. The extracts exhibited significant response for antidiabetic and antiulcer activities. The present study proved the claims of Thespesia populnea mentioned in the Indian System of Medicine.

Keywords

References

  1. Asima Chatterjee and Satyesh Chandra Prakrashi, The Treatise of Indian Medicinal plants.Vol-2. National Institute of Science Communications, New Delhi, India, pp. 188-191 (1992)
  2. Anonymous., The Wealth of India. Vol-X, CSIR, New Delhi, India, pp. 223-225 (1989)
  3. Divakar, M. C., Rao, S. B., Nair, G. R. N, and Hisham, A., The role of fatty acids on the ulcer healing property of the nimbidin fraction of the neem oil. J.Medicinal and Aromatic Plant Science., 23, 404-408, (2001)
  4. Donald J. Ecobichon, The basis of toxicity testing. CRC press, New York, pp. 43-49 (1997)
  5. Ghosh, M. N., Fundamental and Experimental Pharmacology. Scientific Book Agency, Calcutta, India, pp. 191 (1984)
  6. Kirtikar, K. R. and Basu, B. D., Indian Medicinal Plants. Publication and Information Division, Vol 2, CSIR, New Delhi, India, pp. 469-473 (1987)
  7. Kokue, F., Hayama,T., and Hakamue, J. Anti ulcerogenic property of sodium on experimental ulcerations in rats. Jap. J. Phamracol., 24, 621-626 (1974).
  8. Kulkarni, S. R., Hand Book of Experimental Pharmacology. Vallabh Prakasham, New Delhi, India, pp. 148-150 (1990)
  9. Porchezhian S. H., Ansari., E., and Shreedharan, N. K. K., Antihyperglycemic Activity of Euphrasia Officinale leaves. Fitoterapia, 71, 522-526 (2000) https://doi.org/10.1016/S0367-326X(00)00204-5
  10. Rajnarayana, K., Sripal Reddy, M., Chaluvadi, M. R., and Krishna, D. R., Bioflavonoids classification, Pharmacological, Biochemical effects and therapeutic potential. Indian Journal ofPharmacology, 33,2-16 (2001)
  11. Sivarajan, V. V and Indira Balachandran, Ayurvedic Drugs And Their Plant Sources. Oxford and IBH Publishing Co. Pvt. Ltd., New Delhi, India, pp. 352 (1994)
  12. Spiegel, M. R. and Meddis, R., probability and statistics. Me Graw- Hill Book Company, New York, pp. 108-151 (1980)
  13. Tripathi, K. D., Essentials of Medical Pharmacology, Fourth Edition, Jaypee Brothers, Medical Publishers (P) Ltd, New Delhi, India, pp. 279 (1999)
  14. Vaidyaratnam, P. S. Varier, Indian Medicinal Plants. Orient Long man, Vol. 5, pp. 281 (1996)
  15. Yoganarasirnhan, S.N., Medicinal Plants of Indi., Vol-2, Government Siddha Medical College, Tamil Nadu, India, pp. 273 (2000)