Journal of Sasang Constitutional Medicine (사상체질의학회지)

The Society Of Sasang Constitutional Medicine (사상체질의학회)
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Effects of CheongSimYeonJaTang(CSYJT) on Control of Immune-function in highly purified mouse B cells and Mast cell

태음인(太陰人) 청심연자탕(淸心蓮子湯)의 항(抗)allergy 작용(作用)에 대(對)한 실험적(實驗的) 연구(硏究)

  • Park, Seung-Chan (Dept. of Oriental Medicine Graduate School. Taejon University)
  • 박승찬 (대전대학교 한의학과 사상체질의학과학전공)
  • Published : 2003.08.30
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Abstract

In order to evaluate the antiallergic effects of CSYJT, studies were done. We measured the cytotoxic activity for cytokines transcript expression, production of IL-4, IgE, $IFN-{\gamma}$, proliferation of B cell in HRF plus anti-CD40mAb plus rIL-4 stimulated murine splenic B cells. and cytokines transcript expression of IgE in Mast cell The results were obtained as follows: 1. CSYJT decreased the expression of IL-4 in mast cell significantly. 2. CSYJT decreased the production of IL-4 significantly. 3. CSYJT decreased the expression of IgE in mast cell significantly. 4. CSYJT decreased the production of IgE significantly. 5. CSYJT increased the appearance of $IFN-{\gamma}$. The facts above prove that CSYJT is effective against the allergy. Thus, I think that we should study on this continuously.

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