Journal of the Korean Chemical Society (대한화학회지)

Korean Chemical Society (대한화학회)
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Synthesis and Antibacterial Activity of Some Oxazolone Derivatives

옥사졸론 유도체의 합성과 항균성

  • Aaglawe M. J. (Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University) ;
  • S. S. Dhule (Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University) ;
  • S. S. Bahekar (Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University) ;
  • P. S. Wakte (Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University) ;
  • D. B. Shinde (Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University)
  • Published : 2003.04.20
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Abstract

A series of oxazolone derivatives (4a-n) have been synthesized as a potential antibacterial agent. Titled compounds have been prepared by the condensation of aryloxy acetyl-amino-acetic acid with aldehyde in presence of ethanol, acetic anhydride and sodium acetate. The structures of the new compounds were established on the basis of $^1H$ NMR and IR spectral data.

일련의 옥사졸론 유도체들을 (4a-n) 항균제로서 합성하였다. 이 화합물들은 아릴옥시아세틸아미노아세트산을 에탄올, 아세트산 무수물, 아세트산 소듐 존재하에 알데하이드와 반응시켜 합성하였으며 핵자기공명 스펙트럼과 적외선 스펙트럼으로 구조를 확인하였다.

Keywords

References

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