Bulletin of the Korean Chemical Society

  • 제24권3호
  • /
  • Pages.339-344
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  • 2003
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  • 0253-2964(pISSN)
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  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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A Conformational Study of Linkage Positions in Oligosaccharides Investigated by 2-D NMR Spectroscopy and Molecular Modeling

  • 발행 : 2003.03.20
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초록

The conformation of synthetic oligosaccharide can be elucidated by employing molecular modeling and highfield proton NMR (nuclear magnetic resonance) spectroscopy. Information with respect to the composition and configuration of saccharide residues and the sequence and linkage positions of the oligosaccharide can be obtained by employing a variety of one- and two-dimensional NMR techniques and molecular modeling. These techniques are also useful in establishing the solution conformation of the oligosaccharide moiety. This study is focused on the elucidation of linkage positions of synthetic trisaccharides, Gal(β1-4)Glc(β1-3)Glc, Gal(β1-4)Glc(β1-4)Glc and Gal(β1-4)Glc(β1-6)Glc.

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참고문헌

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피인용 문헌

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  2. Development of Fast Synthetic Method and Analytical Technology for Linkage-Isomeric Oligosaccharides vol.277-279, pp.1662-9795, 2005, https://doi.org/10.4028/www.scientific.net/KEM.277-279.33
  3. Applications of Tandem Mass Spectrometry in the Structure Determination of Permethylated Sialic Acid-containing Oligosaccharides vol.26, pp.9, 2003, https://doi.org/10.5012/bkcs.2005.26.9.1347
  4. Molecular Simulations and Conformational Studies of Fucoseα1-3)Gal(β1-X)GlcNAc where X=3, 4, or 6 Oligosaccharides vol.29, pp.9, 2003, https://doi.org/10.5012/bkcs.2008.29.9.1755
  5. A Systematic NMR Determination of α-D-Glucooligosaccharides, Effect of Linkage Type, Anomeric Configuration and Combination of Different Linkages Type on 13C Chemical Shifts for the D vol.30, pp.11, 2003, https://doi.org/10.5012/bkcs.2009.30.11.2535