Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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DEHP Migration Behavior from Excessively Plasticized PVC Sheets

  • Kim, Jung-Hwan (Department of Fiber & Polymer Engineering, Center for Advanced Functional Polymers,Hanyang University) ;
  • Kim, Seong-Hun (Department of Fiber & Polymer Engineering, Center for Advanced Functional Polymers,Hanyang University) ;
  • Lee, Chang-Hyung (Department of Medical Devices & Radiation Health, Korea Food & Drug Administration) ;
  • Nah, Jae-Woon (Department of Polymer Science and Engineering, Sunchon National University) ;
  • Hahn, Airan (Biotechnology & Environmental Eng. Div., Agency for Technology & Standards)
  • Published : 2003.03.20
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Abstract

The quantity, process and kinetics of di-(2-ethylhexyl)phthalate (DEHP) migration in the 30/70 and 40/60 poly(vinylchloride) (PVC)/DEHP blends were investigated using gas chromatograph. A thin and flexible PVC sheet was soaked in surrounding medium (SM) of water/ethanol mixture and acetonitrile with constant stirring to release DEHP. By observed concentration of DEHP in the SM, it is found that acetonitrile is more intense in DEHP migration than water/ethanol mixture. In addition the amount of extracted DEHP is proportional to the leaching temperature and added ratio of DEHP. The behavior of DEHP migration from flexible PVC sheets was described by the Ficks's law with $2.72-10.1\;{times}\;10^{-10}$ cm²/s of the diffusion coefficients.

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References

  1. Jayakrishnan, A.; Sunny, M. C. Polymer 1996, 37, 5213. https://doi.org/10.1016/0032-3861(96)00501-0
  2. Ljunggren, L. Artif. Organs. 1984, 8, 99. https://doi.org/10.1111/j.1525-1594.1984.tb04251.x
  3. Kambia, K.; Dine, T.; Azar, R.; Gressier, B.; Luyckx, M.; Brunet, C. Int. J. Pharm. 2001, 229, 139. https://doi.org/10.1016/S0378-5173(01)00840-7
  4. Parmar, D.; Srivastava, S. P.; Singh, G.; Seth, P. K. Vet. Human Toxicol. 1995, 34, 310.
  5. Jacobson, M. S.; Kevy, S. V.; Parkman, R.; Wesolowski, J. S. Transfusion 1980, 20, 443. https://doi.org/10.1046/j.1537-2995.1980.20480260277.x
  6. Sharman, M.; Read, W. A.; Castle, L.; Gilbert, J. Food Addit. Contam. 1994, 11, 375. https://doi.org/10.1080/02652039409374236
  7. Tomita, I.; Nakamura, Y.; Yagi, K.; Tutikawa, K. Environ. HealthPersp. 1982, 45, 71.
  8. Li, L. H.; Jester, W. F.; Orth, J. M. Toxicol. Appl. Pharm. 1988,153, 258.
  9. Guillette, L. J.; Pickford, D. B.; Crain, D. A.; Rooney, A. A.;Percival, H. F. Gen. Comp. Endocr. 1996, 101, 32. https://doi.org/10.1006/gcen.1996.0005
  10. Messadi, D.; Vergnaud, J. M. J. Appl. Polym. Sci. 1982, 27, 3945. https://doi.org/10.1002/app.1982.070271027
  11. Papaspyrides, C. D. J. Appl. Polym. Sci. 1992, 44, 1145. https://doi.org/10.1002/app.1992.070440703
  12. Steiner, I.; Scharf, L.; Fiala, F.; Washuttl, J. Food Addit. Contam.1998, 15, 812. https://doi.org/10.1080/02652039809374715
  13. Papaspyrides, C. D.; Duvis, T. Polymer 1990, 31, 1085. https://doi.org/10.1016/0032-3861(90)90256-X
  14. Messadi, D.; Vergnaud, J. M. J. Appl. Polym. Sci. 1981, 26, 2315. https://doi.org/10.1002/app.1981.070260718
  15. Labow, R. S.; Tocchi, M.; Rock, G. Transfusion 1986, 26, 351. https://doi.org/10.1046/j.1537-2995.1986.26486262743.x
  16. Rastogi, S. C. Chromatographia 1998, 47, 724. https://doi.org/10.1007/BF02467461
  17. Dine, T.; Luyckx, M.; Cazin, M.; Brunet, C.; Cazin, J. C.;Goudaliez, F. Biomed. Chromatogr. 1991, 5, 94. https://doi.org/10.1002/bmc.1130050211
  18. Fayz, S.; Herbert, R.; Martin, A. J. Pharm. Pharmac. 1977, 29,407. https://doi.org/10.1111/j.2042-7158.1977.tb11354.x
  19. ISO 3826, “Plastics Collapsible Containers for Human Blood andBlood Components”, 1993.

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