Journal of Radiation Protection and Research

The Korean Association for Radiation Protection (대한방사선방어학회)
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Interpretation of Uranium Bioassay Results with the ICRP Respiratory Track and Biokinetic Model

ICRP 호흡기 및 생체역동학적 모델을 이용한 우라늄 생물분석 결과의 해석

  • Kim, H.K. (Dept. of Nuclear Engineering Hanyang University) ;
  • Lee, J.K. (Dept. of Nuclear Engineering Hanyang University)
  • 김현기 (한양대학교 원자력공학과) ;
  • 이재기 (한양대학교 원자력공학과)
  • Published : 2003.03.30
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Abstract

This study describes a practical method for interpretation of bioassay results of inhaled uranium to assess the committed effective doses both for chronic and acute intake situations. Organs in the body were represented by a series of mathematical compartments for analysis of the behavior of uranium in the body according to the gastrointestinal track model, respiratory track model and biokinetic model recommended by the ICRP. An analytical solutions of the system of balance equations among the compartments were obtained using the Birchall's algorithm, and the urinary excretion function and the lung retention function of uranium were obtained. An initial or total intakes by intake modes were calculated by applying excretion and retention functions to the urinary uranium concentration and the lung burden measured with a lung counter. The dose coefficients given in ICRP 78 are used to estimate the committed effective doses from the calculated intakes.

본 연구는 호흡을 통해 우라늄을 만성 또는 급성섭취한 경우 생물분석 결과의 해석을 통해 예탁유효선량을 평가하는 실질적인 방법을 기술하고 있다. 인체에서의 우라늄 거동의 해석을 위해 인체의 장기를 ICRP에서 권고하는 소화기 모델, 호흡기 모델 그리고 생체역동학적 모델에 따라 일련의 수학적 격실로 구성하였다. Birchall의 알고리듬을 이용하여 각 격실에서의 균형방정식의 해석적인 해를 얻었으며 우라늄의 소변 배설함수와 폐 잔류함수를 획득하였다. 소변 중 우라늄 농도와 폐 계수기로 측정된 폐 부하량에 각각 배설 및 잔류함수를 적용하여 섭취모드에 따른 초기 섭취량 또는 총 섭취량을 계산하였다. 예탁유효선량은 ICRP 78에서 제공하는 선량 환산계수를 계산된 섭취량에 적용함으로써 평가된다.

Keywords

References

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