Treatment Results for Adenoid Cystic Carcinoma of the Major Salivary Gland

주타액선에서 발생한 선양낭세포암종의 방사선치료성적

  • Lee Sang-Wook (Departments of Radiation Oncology, Yonsei University College of Medicine, Yonsei Cancer Center) ;
  • Kim Gwi-Eon (Departments of Radiation Oncology, Yonsei University College of Medicine, Yonsei Cancer Center) ;
  • Park Cheong-Soo (Departments of Otolaryngology, Yonsei University College of Medicine, Yonsei Cancer Center) ;
  • Choi Eun-Chang (Department of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Lee Kang-Kyoo (Department of Radiation Oncology, Yonsei University Wonju College of Medicine) ;
  • Park Won (Departments of Radiation Oncology, Yonsei University College of Medicine, Yonsei Cancer Center) ;
  • Suh Chang-Ok (Departments of Radiation Oncology, Yonsei University College of Medicine, Yonsei Cancer Center)
  • 이상욱 (연세대학교 의과대학 방사선종양학교실) ;
  • 김귀언 (연세대학교 의과대학 방사선종양학교실) ;
  • 박정수 (연세대학교 의과대학 외과학교실) ;
  • 최은창 (연세대학교 의과대학 이비인후과학교실) ;
  • 이강규 (연세대학교 원주의과대학 방사선종양학교실) ;
  • 박원 (연세대학교 의과대학 방사선종양학교실) ;
  • 서창옥 (연세대학교 의과대학 방사선종양학교실)
  • Published : 2002.11.01

Abstract

Purpose: This study was to investigate clinical feature of adenoid cystic carcinoma (ACC) in the major salivary gland. Materials and Methods: A retrospective analysis was undertaken for 23 patients with adenoid cystic carcinoma of the major salivary gland, who completed postoperative radiotherapy at the Yonsei Cancer Center, Yonsei University Hospital between May 1981 and December 1999. The male to female ratio was 1.1:1. Median age was 50. Follow up periods were 12-180 months with the median follow-up time of 59 months. Results: Parotid gland, submandibular gland and sublingual gland were 17, 5 and 1 respectively. Overall failure rate was 26%. Local failure was observed in two patients with parotid gland origin. Five cases showed distant failure. Overall and disease free survival rate were 68% and 72% respectively. Conclusion: Major pattern of failure was distant failure. Resection margin status had not prognostic significance. Postoperative radiation treatment is an effective to control in the adenoid cystic carcinoma of the major salivary gland.

Keywords

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