A Clinical Analysis of Major Salivary Gland Tumors

주타액선 종양의 임상적 고찰

  • Yoo Young-Sam (Department of Otolaryngology, Inje University School of Medcine) ;
  • Woo Hun-Young (Department of Otolaryngology, Inje University School of Medcine) ;
  • Yun Ja-Bok (Department of Otolaryngology, Inje University School of Medcine) ;
  • Choi Jeong-Hwan (Department of Otolaryngology, Inje University School of Medcine) ;
  • Jo Kyung-Rai (Department of Otolaryngology, Inje University School of Medcine) ;
  • Chung Sang-Won (Department of Otolaryngology, Inje University School of Medcine) ;
  • Han Dong-Hoon (Department of Otolaryngology, Inje University School of Medcine)
  • 유영삼 (인제대학교 의과대학 상계백병원 이비인후과학교실) ;
  • 우훈영 (인제대학교 의과대학 상계백병원 이비인후과학교실) ;
  • 윤자복 (인제대학교 의과대학 상계백병원 이비인후과학교실) ;
  • 최정환 (인제대학교 의과대학 상계백병원 이비인후과학교실) ;
  • 조경래 (인제대학교 의과대학 상계백병원 이비인후과학교실) ;
  • 정상원 (인제대학교 의과대학 상계백병원 이비인후과학교실) ;
  • 한동훈 (인제대학교 의과대학 상계백병원 이비인후과학교실)
  • Published : 2002.05.01

Abstract

Background and Objective: Even though major salivary gland tumor is a rare disease, the diversity of histopathologic characteristics makes treatment decisions difficult. The aim of this study is to analysis the clinical experience of our major salivary gland tumor and to suggest a guideline of treatment. Materials and Method: Sixty-eight major salivary gland tumors and tumor-like glandular enlargements treated at Sanggye Paik Hospital during the past seven years between June, 1995 and January, 2002 are analyzed for histopathologic diagnosis, treatment modality, clinical manifestation, local control, and treatment-related morbidity, recurrence rate, retrospectively. Results: In twenty-eight patients the swellings were diagnosed as non-tumorous condition. The clinical features, diagnostic and surgical management of fourty salivary neoplasms involving the parotid and submandibular glands are correlated with their histological features. Conclusion: We have concluded that salivary gland neoplasms are needed multimodal treatment, because of their highly variable biologic behavior in each tumor type. Thirty-four cases were benign and six cases were malignant. Most of benign cases were pleomorphic adenoma and they showed wide age-distribution. In six malignant cases, there were acinic cell carcinoma, adenocarcinoma, carcinoma ex-plemorphic adenoma, myoepithelioma, and adenoid cystic carcinoma.

Keywords

References

  1. Bardwill JM : Tumors ofparotid gland. Am J Sung. 1976 ; 35 : 104-107
  2. Spiro RH : Salivary neoplasm. overview of a 35 years experience with 2807 patients. Head Neck Surg. 1986 ; 8 : 177-184 https://doi.org/10.1002/hed.2890080309
  3. Eneroth eM: Salivary gland tumors in the parotid, submandibular gland and the palatal lesion. Cancer. 1971 ; 27 : 1415-1417 https://doi.org/10.1002/1097-0142(197106)27:6<1415::AID-CNCR2820270622>3.0.CO;2-X
  4. Spiro RH, Huvos AG, Strong EW : Cancer ofthe parotid gland. Am J Sung. 1975 ; 130 (4) : 452-9 https://doi.org/10.1016/0002-9610(75)90483-3
  5. Hom-Ross DL, Ljung BM, MorrIo M : Environmental factirs and the risk of salivary gland cancer. Epidemiology. 1997 ; 8(4) : 414-419 https://doi.org/10.1097/00001648-199707000-00011
  6. Maran AGE : Recurrent pleomorphic adenomas of the parotid gland. Arch Otolaryngo. 1974 ; 110 : 107