A Case of n-Hexane Induced Neuropathy with Focal Conduction Block

국소적 전도차단을 보인 n-Hexane induced neuropathy 1례

  • Seo, Wookeun (Department of Neurology, College of Medicine, Korea University) ;
  • Park, Beom-Sik (Department of Neurology, College of Medicine, Korea University) ;
  • Cho, Seong Jin (Department of Pathology, College of Medicine, Korea University) ;
  • Jhun, Hyung-Jun (Department of Occupational and Environmental Medicine, College of Medicine, Korea University) ;
  • Koh, Seong-Beom (Department of Neurology, College of Medicine, Korea University) ;
  • Kim, Byung-Jo (Department of Neurology, College of Medicine, Korea University) ;
  • Park, Jong-Tae (Department of Occupational and Environmental Medicine, College of Medicine, Korea University) ;
  • Park, Min-Kyu (Department of Neurology, College of Medicine, Korea University) ;
  • Park, Kun-Woo (Department of Neurology, College of Medicine, Korea University) ;
  • Lee, Dae-Hie (Department of Neurology, College of Medicine, Korea University)
  • 서우근 (고려대학교 의과대학 신경과학교실) ;
  • 박범식 (고려대학교 의과대학 신경과학교실) ;
  • 조성진 (고려대학교 의과대학 해부병리학교실) ;
  • 전형준 (고려대학교 의과대학 산업의학교실) ;
  • 고성범 (고려대학교 의과대학 신경과학교실) ;
  • 김병조 (고려대학교 의과대학 신경과학교실) ;
  • 박종태 (고려대학교 의과대학 산업의학교실) ;
  • 박민규 (고려대학교 의과대학 신경과학교실) ;
  • 박건우 (고려대학교 의과대학 신경과학교실) ;
  • 이대희 (고려대학교 의과대학 신경과학교실)
  • Published : 2002.05.01

Abstract

A 32-year-old man who had worked at aluminum processing plant for 4 months visited us. He complained of numbness and paresthesia of both foot and hands and weakness of all extremities. Electrophysiologic study showed motorsensory polyneuropathy of diffuse axonal type with focal conduction block. And we discovered higher concentration of n-Hexane in his workplace. On sural nerve biopsy, bubbly enlarged nerve fibers in light microscope and thick myelin sheath and axonal degeneration on electron microscope were found. We diagnosed it as n-Hexane induced neuropathy.

Keywords