Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Combined Regional Variant of Guillain-Barre Syndrome with Paralysis of Pupils and Optic neuritis

동공마비와 시신경염이 동반된 길랑-바레 증후군 이형

  • Lee, Byeung-Yong (Department of Neurology, Chonbuk National University Medical School Research Institute of Clinical Medicine, Chonbuk National University) ;
  • Oh, Sun-Young (Department of Neurology, Chonbuk National University Medical School Research Institute of Clinical Medicine, Chonbuk National University) ;
  • Seo, Man-Wook (Department of Neurology, Chonbuk National University Medical School Research Institute of Clinical Medicine, Chonbuk National University) ;
  • Kim, Young-Hyun (Department of Neurology, Chonbuk National University Medical School Research Institute of Clinical Medicine, Chonbuk National University) ;
  • Shin, Byoung-Soo (Department of Neurology, Chonbuk National University Medical School Research Institute of Clinical Medicine, Chonbuk National University)
  • 이병용 (전북대학교 의과대학 신경과학교실, 전북대학교 임상의학연구소) ;
  • 오선영 (전북대학교 의과대학 신경과학교실, 전북대학교 임상의학연구소) ;
  • 서만욱 (전북대학교 의과대학 신경과학교실, 전북대학교 임상의학연구소) ;
  • 김영현 (전북대학교 의과대학 신경과학교실, 전북대학교 임상의학연구소) ;
  • 신병수 (전북대학교 의과대학 신경과학교실, 전북대학교 임상의학연구소)
  • Published : 2002.05.01
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Abstract

Two separate cranial nerve variants of Guillain-Barre syndrome(GBS) have been reported. One is Miller-Fisher syndrome, the other is polyneuritis cranialis. Involvement of the extraocular muscles in variants of GBS is well recognized, but complete external and internal opthalmoplegia is rare. Optic neuritis remains the only consistent, albeit very uncommon, evidence of inflammation of central nervous system myelin in GBS. This propose that GBS is part of a spectrum of central and peripheral inflammation. This case is an unusual clinical variant who had ptosis, opthalmoplegia, areflexia, ataxia, optic neurritis, marked oropharyngeal, and neck and shoulder weakness. This combined regional from is able to misdiagnose initially as botulism or diphtheria and less so, myasthenia. So if we were consider variant from of GBS, it is possible for make a correct diagnosis more easily and treatment without delay.

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