Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Changes of Electroencephalography & Cognitive Function in Subjects with White Matter Degeneration

대뇌 백질 변성을 보인 환자에서의 뇌파와 인지기능의 변화

  • Kwon, Do-Hyoung (Department of Neurology, College of Medicine, Chungnam National University) ;
  • Yu, Sung-Dong (Department of Neurology, College of Medicine, Chungnam National University) ;
  • Lee, Ae-Young (Department of Neurology, College of Medicine, Chungnam National University)
  • 권도형 (충남대학교 의과대학 신경과학교실) ;
  • 유성동 (충남대학교 의과대학 신경과학교실) ;
  • 이애영 (충남대학교 의과대학 신경과학교실)
  • Published : 2002.05.01
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Abstract

Background : Spatial analysis of EEG is a phenomenal assessment and not so informative for phase space and dynamic aspect of EEG data. In contrast, nonlinear EEG analysis attempts to characterize the dynamics of neural networks in the brain. We have analyzed the features of EEG nonlinearly in subjects with white matter change on brain MRI and compared the results with cognitive function in each. Methods : Digital EEG data were taken for 30 seconds in 9 subjects with white matter degeneration and in 5 healthy normal controls without white matter change on MRI. Then we analyzed them nonlinearly to calculate the correlation dimension(D2) using the MATLAB software. The cognitive function was assessed by 3MS(modified mini-mental state examination). The severity of white matter change was assessed by Scheltens scale. Results : The mean D2 value of normal control was greater than that of white matter degeneration group. The D2s of some channels were correlative with 3MS and degree of white matter degeneration significantly. Conclusions : nonlinear analysis of EEG can be used as one of adjuvant functional studies for prediction of cognitive impairment in subjects with white matter degeneration and subcortical white matter change can be influential on cognitive function and correlation dimension of EEG.

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