Journal of Acupuncture Research
- Volume 19 Issue 2
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- Pages.65-77
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- 2002
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- 2586-288X(pISSN)
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- 2586-2898(eISSN)
The Study on the Cytotoxicity of Compounds of Bee Venom for Herb-Acupuncture
봉독(蜂毒) 약침액(藥鍼液)의 세포독성(細胞毒性)에 관(關)한 연구(硏究)
- Park, Won (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-Hee University) ;
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Kim, Yong-Suk
(Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-Hee University) ;
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Koh, Hyung-Kyun
(Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-Hee University)
- Received : 2002.02.28
- Accepted : 2002.03.18
- Published : 2002.04.20
Abstract
Objective : This study was undertaken to determine which compound of Bee Venom for herb-acupuncture has cytotoxicity on mouse mast cell line. Methods : We compared crude bee venom and its compounds such as melittin, mast cell degranulating peptide (MCD peptide), apamin with control groups on cytotoxicity by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Results & Conclusion : 1. Crude bee venom showed significant cytotoxic effect(p<0.01) in 1 hour treatment with