Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
권호 표지

T lymphocyte response to periodontal complex bacterial biofilm

치주복합세균성 바이오필름에 대한 T 임파구 반응

  • Choi, Jeom-IL (Department of Periodontology, School of Dentistry, Pusan National University) ;
  • Kim, Sung-Jo (Department of Periodontology, School of Dentistry, Pusan National University) ;
  • Kim, Su-Jin (Department of Periodontology, School of Dentistry, Pusan National University)
  • 최점일 (부산대학교 치과대학 치주과학교실) ;
  • 김성조 (부산대학교 치과대학 치주과학교실) ;
  • 김수진 (부산대학교 치과대학 치주과학교실)
  • Published : 2002.03.30
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Abstract

본 연구는 P. gingivalis biofilm을 쥐에 면역했을 경우 숙주의 면역체계중에서 T 임파구가 어떻게 반응하는가를 비교연구한 것으로 P. gingivalis biofilm은 단일 세균으로 구성된 것과, F. nucleatum과 복합된 것 공히 T 임파구가 유리하는 cytokine 중에서 IFN-gamma의 현저한 감소를 초래하는 것으로 판명되어, 향후 숙주 면역방어체계에 미치는 영향을 연구하는 중요한 지침자료를 제공해 주었다.

Keywords

References

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