Determination of Inorganic Elements in Women Blood Serum using Instrumental Neutron Activation Analysis

중성자방사화분석법을 이용한 성인여성 혈청중의 무기 원소 분석

  • Received : 2002.07.15
  • Published : 2002.12.25

Abstract

In this study, instrumental neutron activation analysis was used to assess the concentration level of inorganic trace elements in Korean women blood serum. It was found out that high concentration of Na and Cl incurs analytical interference, but 12 elements of Br, Ca, Cl, Co, Cr, Cs, Fe, K, Na, Rb, Se, Zn can be determined under the condition of interference minimization. Serum samples collected from 63 women were analyzed and the concentration level and range of the elements were evaluated. NIST SRMs were analyzed simultaneously for analytical quality control. The average values of Na and Cl determined in serum samples are around 3000 mg/L, Ca is 100 mg/L and K is 200 mg/L. Besides, Br, Se and Zn have concentration level of 6.0, 0.1 and 1.0 mg/L, respectively. It was found that there is no significant difference between the present values and reported values.

본 연구는 우리나라 성인여성의 혈청 내 미량 무기 원소의 농도를 조사하기 위해 중성자 방사화 분석법을 적용하였다. 혈청시료중의 나트륨과 염소의 높은 농도가 분석에 제헌을 주었으며 이들의 간섭을 최소화시킨 분석조건에서 Br, Ca, Cl, Co, Cr, Cs, Fe, K, Na, Rb, Se, Zn 와 같은 12종 원소의 분석이 가능하였다. 63명의 성인여성으로부터 채취한 혈청시료를 분석시료를 분석하여 각 원소의 농도수준과 범위 등을 결정하였으며 미국표준연구소의 표준물질들을 혈청시료와 동시에 분석하여 분석품질관리에 사용하였다. 혈청시료중의 무기질원소들의 평균값은 Na 과 Cl은 약 3000 mg/L, Ca은 약 100 mg/L, K은 200 mg/L, Br, Se 및 Zn은 각각 6.0, 0.1, 1.0 mg/L 등의 농도수준을 보였으며 지금까지 보고된 값과 비교한 결과 큰 차이를 보이지 않았다.

Keywords

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