분석과학 (Analytical Science and Technology)

  • 제15권3호
  • /
  • Pages.270-286
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  • 2002
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  • 1225-0163(pISSN)
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  • 2288-8985(eISSN)
한국분석과학회 (The Korean Society of Analytical Sciences)
권호 표지

다이옥신류에 의한 한국인의 폭로 현황 및 리스크 평가

Residue and Risk Assessment of Polychlorinated dibenzo-p-dioxin/dibenzofurans in the Korean Population

  • 투고 : 2001.10.17
  • 발행 : 2002.06.25
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초록

서울, 마산 그리고 진주 지역에 거주하는 일반인 체내에 잔류하는 PCDDs/DFs의 축적 레벨은 독성등량으로 환산하여 PCDDs가 평균 9 pg I-TEQ/g(0.2 ~ 30 pg TEQ/g 지방 중량), PCDFs가 8 pg I-TEQ/g (0.8 ~ 25 pg TEQ/g)으로 계산되어졌다. 한편 마산 지역에서 채취된 모유 샘플의 경우 PCDDs가 평균 13 pg I-TEQ/g (lipid wt.), PCDFs가 평균 4.8 pg I-TEQ/g으로 각각 검출되어졌다. 전반적으로 한국인 체내의 PCDDs/DFs의 잔류레벨은 구미 선진국과 비교하여 낮은 수준임을 확인 할 수 있었다. 유아에 있어 수유를 통한 PCDDs/DFs의 일일 폭로량은 유아 체중을 5 kg, 일일 모유 섭취량을 800 mL 로 가정하여 계산되어졌으며, 그 계산 결과 유아의 2,3,7,8-TeCDD의 폭로량은 39 pg/kg body weight/day 이었으며, 총 TEQ로 환산 할 경우 86 pg/kg/day로 계산되어졌다. 이러한 폭로 레벨은 미국의 실질 안전계수(0.001 pg/kg/day) 혹은 WHO가 설정한 TDI(4 pg/kg/day)를 훨씬 초과하는 수준으로, 단기간이지만 수유기에 이루어지는 다량의 PCDDs/DFs의 폭로에 대한 적절한 리스크 평가와 대책 마련이 필요한 것으로 사료된다.

The human adipose and milk samples analyzed in this study were collected at hospitals in Seoul, Masan and Jinju. The mean values of International Dioxin Toxic Equivalents (I-TEQ) of PCDDs and PCDFs in human adipose samples from the three regions were calculated as 9 pg I-TEQ/g(0.2 ~ 30 pg TEQ/g, lipid weight basis) and 8 pg I-TEQ/g (0.8 ~ 25 pg TEQ/g), respectively. The residue levels of PCDDs-TEQ and PCDFs-TEQ in human milk collected from Masan were 13 pg I-TEQ/g (lipid wt.) and 4.8 pg I-TEQ/g, respectively. On the whole, the contamination levels of these compounds in the Korean population were lower than those in the other countries. Based on the analytical data and assuming a daily intake consumption of 800 mL milk with 3% fat, the average daily intake of PCDDs/DFs via human milk for a baby weighing 5 Kg could be calculated. The daily intake of PCDDs/DFs via breast-feeding was estimated to be 39 pg/kg body weight/day for 2,3,7,8-TeCDD and 86 pg/kg/day for TEQ. These levels are far above all virtually safe dose(VSD) or tolerable daily intake(TDI) values proposed by health authorities in various countries, ranging from 0.001(US EPA) to 4 pg/kag/day (WHO).

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