갑상선암 환자에서 전종격동의 전이성 암처럼 보이는 흉선의 방사성옥소 섭취

Thymic Radioiodine Uptake Mimicking Metastatic Papillary Carcinoma in the Anterior Mediastinum

  • 박찬희 (아주대학교 의과대학 핵의학과) ;
  • 이명훈 (아주대학교 의과대학 핵의학과)
  • Park, Chan-H. (Department of Nuclear Medicine School of Medicine, Ajou University) ;
  • Lee, Myoung-Hoon (Department of Nuclear Medicine School of Medicine, Ajou University)
  • 발행 : 2002.02.28

초록

A 30 year-old female patient with papillary thyroid carcinoma received her fifth radioiodine ablation therapy after the subtotal thyroidectomy. The scan, which was peformed one week after the last therapy, revealed residual uptake in the thyroid bed and uptake in the anterior mediastinum suggesting metastasis. However, further evaluation of the thorax with chest CT and camera-based FDG PET confirmed normal thymus without metastatic focus. Occasionally thymus remains intact in adult and has avidity for I-131 and FDG. Therefore, normal thymus (instead of metastasis) should be considered in patients with well differentiated thyroid carcinoma and anterior mediastinal radioiodine uptake.

키워드

참고문헌

  1. Vermiglio F, Baudin E, Travagli JP, et al: Iodineconcentration by the thymus in thyroid carcinoma. JNue!e Med 1996;37:1830.
  2. Bestagno M, Pagliani R, Maira G, et al: Mediastinaluptake of 1-131 in patients with thyroid cancer: Mayit be reffered to normal thymus? Eur J Nue! Med1993;20:648.
  3. Veronikis IE, Simkin P, Braverman LE: Thymicuptake of iodine-131 in the anterior mediastinum. JNue! Med 1996;37:991.
  4. Wilson LM, Barrington SF, Morrison ID, et al:Therapeutic implications of thymic uptake ofradioiodine in thyroid carcinoma. Eur J Nue! Med1998;25:622.
  5. Davidson J, McDougall: How frequently is thethymus seen on whole-body iodine-131 diagnosticand post-treatment scans? Eur J Nue! Med2000;27:425.
  6. Alibazoglu H, Alibazoglu B, Hollinger E, et al.:Normal thymic uptake of 2-deoxy-2[F-18]fluoro-Dglucose.Clin Nue! Med 1999;24:597.