Clinical and Experimental Reproductive Medicine

  • 제29권4호
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  • Pages.279-285
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  • 2002
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  • 2233-8233(pISSN)
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  • 2233-8241(eISSN)
대한생식의학회 (The Korean Society for Reproductive Medicine)
권호 표지

난소적출술 환자에서 Estrogen 단독요법 및 Estrogen-androgen 병합요법에 관한 연구

A Study of Estrogen only Therapy and Estrogen Plus Androgen Combination Therapy in Surgical Menopause Patients

  • 배광범 (서울대학교 의과대학 산부인과학교실)
  • Bai, Kwang-Bum (Department of Obstetrics and Gynecology, College of Medicine, Seoul National University)
  • 발행 : 2002.12.30
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초록

Objective : To evaluate the difference between estrogen only therapy and estrogen-androgen combination therapy in surgical menopause patients. Materials and Method: Surgical menopause patients received 0.625 mg conjugated equine estrogens or 0.625 mg conjugated equine estrogens plus 1.25 mg methyltestosterone for 2 years. Bone mineral density, menopausal symptoms, lipoprotein profiles were measured. Results: Both groups showed increased bone mineral density. In the combination group, total cholestero l, high density lipoprotein cholesterol and triglycerides decreased. In the estrogen only group, low density lipoprotein cholesterol decreased but high density lipoprotein cholesterol increased significantly. In both groups, menopausal symptoms were much improved. Side effects were easily tolerated in both groups. Conclusions: Estrogen-androgen combination therapy had comparable benefits compared with estrogen only therapy.

키워드

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