Journal of Photoscience
- Volume 9 Issue 2
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- Pages.138-141
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- 2002
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- 1225-8555(pISSN)
Artificial Radical Generating and Scavenging Systems: Synthesis and Utilization of Photo-Fenton Regent in Biological Systems
- Matsugo, Seiichi (Department of Applied Chemistry & Biotechnology, Faculty of Engineering, Yamanashi University)
- Published : 2002.08.01
Abstract
A photo-labile compound which is bioinactive but, upon irradiation with light, yields bioactive species is called as "caged compound". Photolysis of caged compounds generating bioactive species, has become a general method to produce a desired amounts of bioactive species in the specific time interval at the desired place or area of the target biological systems. For this purpose, we designed and synthesized caged hydroxyl radical., "Photo-Fenton Reagent" NP-IIl. NP-IIl has a strong absorption maximum at 377 nm and yields hydroxyl radicals upon UV light irradiation. The antioxidant activity of the