Archives of Pharmacal Research

  • 제25권6호
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  • Pages.837-841
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  • 2002
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  • 0253-6269(pISSN)
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  • 1976-3786(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Four New Acetylated Ginsenosides from Processed Ginseng(Sun Ginseng)

  • Park, Il-Ho (Research Institute of Pharmaceutical Sciences and Ginseng Science Research Institute, College of Pharmacy, Seoul National University) ;
  • Han, Sang-Beom (Seoul Clinical Laboratories) ;
  • Kim, Jong-Moon (Research Institute of Pharmaceutical Sciences, College of Pharmacy, College of Pharmacy, Seoul National University) ;
  • Piao, Longzhu (Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University) ;
  • Kwon, Sung-Won (Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University) ;
  • Kim, Na-Young (Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University) ;
  • Kang, Tak-Lim (College of Oriental Medicine, Taejon University) ;
  • Park, Man-Ki (Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University) ;
  • Park, Jeong-Hill (Research Institute of Pharmaceutical Sciences and Ginseng Science Research Institute, College of Pharmacy, Seoul National University)
  • 발행 : 2002.12.01
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초록

Four new acetylated ginsenosides were isolated from the processed ginseng (SG, sun ginseng). Their structures were determined to be $3{\beta},{\;}12{\beta}-dihydroxydammar-20(22),24-diene-3-O-{\beta}-D-glucopyranosyl(1{\rightarrow}2)-{\beta}-D-6"-O-acetylglucopyranoside;{\;}3{\beta},12{\beta}-dihydroxydammar-20(21),{\;}24-diene-3-O-{\beta}-D-glucopyranosyl(1{\rightarrow}2)-{\beta}-D-6"-O-acetylglucopyranoside;{\;}3{\beta},{\;}6{\alpha},12{\beta}-trihydroxydammar-20(22),24-diene-6-O-{\beta}-D-6'-O-acetylglucopyranoside{\;}and{\;}3{\beta},6{\alpha},12{\beta}-trihydroxydammar-20(21),24-diene-6-O-{\beta}-D-6'-O-acetylglucopyranoside$ based on spectroscopic evidences. The compounds were named ginsenoside $Rs_4,{\;}Rs_5,{\;}RS_6{\;}and{\;}Rs_7$, respectively.pectively.

키워드

참고문헌

  1. Han, D.S., Pharmacognogy. Dong Myoung Sa, Seoul, 1988
  2. Keum, Y. S., Park, K. K., Lee, J. M., Chun, K. S., Park, J. H., Lee, S. K., Kwon, H. J. and Surh, Y. J., Antioxidant and antitumor promoting activities of the methanol extract of heat-processed ginseng, Cancer Letters, 150, 41-48 (2000) https://doi.org/10.1016/S0304-3835(99)00369-9
  3. Kim, S. I., Park, J. H., Ryu, J. H., Park, J. D., Lee, Y. H., Park, J. H., Kim, T. H., Kim, J. M. and Baek, N. I., Ginsenoside $Rg_5$, A Genuine Dammarane Glycoside from Korean Red Ginseng, Arch. Pharm. Res., 19, 551-553 (1996) https://doi.org/10.1007/BF02986026
  4. Kim, W. Y, Kim, J. M., Han, S. B., Lee, S. K., Kim, N. D., Park, M. K., Kim, C. K., Park, J. H., Steaming of Ginseng at High Temperature Enhances Biological Activity, J. Nat. Prod., 63, 1702-1704 (2000) https://doi.org/10.1021/np990152b
  5. Kitagawa, I., Yoshikawa, M., Yoshigara, M., Hayashi, T. and Taniyama, T, Chemical Studies on Crude Drug Precession. I. On the Constitution of Ginseng Radix Rubra (1), Yakugaku Zasshi, 103, 612-622 (1983) https://doi.org/10.1248/yakushi1947.103.6_612
  6. Park, I. H., Kim, N. Y, Han, S. B., Kim, J. M., Kwon, S. W., Kim, H. J., Park, M. K., Park, J. H., Three new dammarane glycosides from heat processed ginseng, Arch. Pharm. Res., 25, 428-432 (2002) https://doi.org/10.1007/BF02976595
  7. Ryu, J. H., Park, J. H., Eun, J. H., Jung, J. H. and Sohn, D. H., A dammarane glycoside from Korean red ginseng, Phytochemistry, 44, 931-933 (1997) https://doi.org/10.1016/S0031-9422(96)00661-9
  8. The society for Korean Ginseng, Understanding of Korean Ginseng, Seoul, 1995