Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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13-Hydroxy-9Z,11E,15E-octadecatrienoic Acid from the Leaves of Cucurbita moschata

  • Bang, Myun-Ho (Graduate School of Biotechnology ＆ Plant Metabolism Research Center) ;
  • Han, Jae-Taek (Graduate School of Biotechnology ＆ Plant Metabolism Research Center) ;
  • Kim, Hae-Yeong (Graduate School of Biotechnology ＆ Plant Metabolism Research Center) ;
  • Park, Young-Doo (Graduate School of Biotechnology ＆ Plant Metabolism Research Center) ;
  • Park, Chang-Ho (Department of Chemical Engineering, Kyunghee University) ;
  • Lee, Kang-Ro (College of Pharmacy, Sung Kyun Kwan University) ;
  • Baek, Nam-In (Graduate School of Biotechnology ＆ Plant Metabolism Research Center)
  • Published : 2002.08.01
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Abstract

A new unsaturated hydroxy fatty acid was isolated from the leaves of Cucurbita moschata through repeated silica gel column chromatography and chemical methods. The structure of the new fatty acid was determined as 13-hydroxy-9, 11, 15-octadecatrienoic acid on the basis of several spectral data including 2D-NMR. The stererostructures of double bonds were determined to be 9Z, 11 E and 15E by coupling patterns of related proton signals in the $^1H-NMR$ and NOESY experiments.

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References

  1. Chisholm, M. J., and Hopkins, C. Y., Fatty Acid Composition of Some Cucurbitaceae Seed Oils. Can. J. Chem., 42, 560-564 (1964) https://doi.org/10.1139/v64-082
  2. Chisholm, M. J., and Hopkins, C. Y., Fatty Acids of Catalpa bignonioides and Other Bignoniaceae Seed Oils. Can. J. Chem., 43, 2566-2570 (1965) https://doi.org/10.1139/v65-352
  3. Han, J. T., Ahn, E.-M., and Baek, N.-I., Development of Biologically Active Compounds from Edible Plant Sources-II. Isolation of Fatty Acids and Sterol Glycosides from the Leaves of Cucurbita moschata DUCH. J. Korean Soc. Agric. Chem. Biotechnol., 42, 267-270 (1999)
  4. Hopkins, C. Y., Chisholm, M. J., and Ogrodnik, J. A., Identity and Configuration of Conjugated Fatty Acids in Certain Seed Oils. Lipids, 4, 89-92 (1968) https://doi.org/10.1007/BF02531923
  5. Smith, Jr., C. R., and Wolff, I., Characterization of Naturally Occurring $\alpha$-Hydroxylinolenic Acid. Lipids, 4, 9-14 (1968) https://doi.org/10.1007/BF02531787