References
- Moncada, S., Palmer, R. M. and Higgs, E. A. : Nitric oxide: physiology. pathophysiology, and pharmacology. Pharmacol. Rev. 43, 109 (1991)
- Nathan, C. : Nitric oxideas a secretory product of mammalian cells. FASEB J. 6, 3051 (1992)
- Knowles, R. G. and Mocada, S. : Nitric oxide as a signal in blood vessels. TIBS. 17, 399 (1992)
- Stuehr, H. H. J., Kwon, N. S., Weise, M. and Nathan, C. : Purification of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein. Proc. Natl. Sci. USA. 88, 7771(1991)
- McCartney-Francis, N., Allen, J. B., Mizel, D. E., Albina, J. E., Xie, Q. W., Nathan, C. F. and Wahl, S. M. : Suppression of arthritis by an inhibitor of nitric oxide synthase. J. Exp. Med. 178, 749 (1993) https://doi.org/10.1084/jem.178.2.749
-
Weisz, A., Cicatiello, I. and Esumi, H. : Regulation of the mouse inducible-type nitric oxide synthase gene promoter by interferon-gamma, bacterial lipopolysaccharide and
$N^{G}$ - moonomethyl-L-arginine. Biochem. J. 316, 209 (1996) - Duerksen-Hughes, P. J., Day, D., Laster, S. M. A., Zacharidaes, N. A., Aquino, L. and Gooding, L. R. : Both tumor necrosis factor and nitric oxide participate in lysis of simian virus 40-transformed cells by activated macrophages J. Immunol. 149, 2114 (1992)
- Willeaume, V., Kruys, V., Mijatovic, T. and Huez, G. : Tumor necrosis factor-alpha production induced by viruses and by lipopolysaccharides in macrophages: similarities and differences. J. Inflamm. 46, 1 (1995)
- Choi, O. J. : Usage and Constituents of Medicinal Plants. Ilweolseogak, Seoul, p. 62 (1991)
- Kuhara, K, Takanashi, H., Hirono, I., Furuya, T. and Asada, Y. : Carcinogenic activity of clivorine, a pyrrolizidine alkaloid isolated from Ligularia dentata. Cancer Lett. 10, 117 (1980) https://doi.org/10.1016/0304-3835(80)90034-8
- Wang, W. S., Gao, K., Yang, L. and Jia, Z., J. : Eremophilenolides from Ligularia fischeri. Planta Med. 66, 189 (2000)
- Kim, Y. K., Kim, R. G., Park, S. J., HA, J. H., Choi, J. W., Park H. J. and Lee, K. T. : In vitro antiinflammatory activity of kalopanaxsaponin A isolated from Kalopanax pictus in murine macrophage RAW 264.7 cells. Biol Pharm Bull. 25, 472 (2002)
- Park. H. J., Lee, K. T., Jung, W. T., Choi, J. W. and Kadota, S. : Protective Effects of syringin isolated from Kalopanax pictus on galactosamine induced hepatotoxicity, Natural Medicine. 53, 113 (1999)
- Vane, J. R. : Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New. Biol. 23, 232 (1971)
- Funk, C. D., Frunk, L. B., Kennedy, M. E., Pong, A. S. and Fitzgerald, G. A. : Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment. FASEB J. 5, 2304 (1991)
- Seibert, K., Zhang, Y., Leahy, K., Hauser, S., Masferrer, J., Perkins, W., Lee, L. and Ksakson, P. : Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc. Natl. Acad. Sci. U.S.A 91, 12013 (1994)
- Masferrer, J., Zweifel B. S., Manning, P. T., Hauser, S. D., Leahy, K. M., Smith, W. G., Isakson, P. C. and Seibert, K. : Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. Proc. Natl. Acad. Sci. U.S.A. 91, 3228 (1994) https://doi.org/10.1073/pnas.91.8.3228
- Feldmann, M., Brennan, F. M. and Maini, R. N. : Role of cytokines in rheumatoid arthritis. Annu. Rev. Immunol. 14, 397 (1996) https://doi.org/10.1146/annurev.immunol.14.1.397
- Harada, A., Sekido, N., Akahoshi, T., Wada,T., Mukaida, N. and Matsushima, K. J.: Essential involvement of interleukin-8 (IL-8) in acute inflammation. J. Leukoc. Biol. 56, 559 (1994)