Toxicological Research

  • 제18권4호
  • /
  • Pages.397-400
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  • 2002
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  • 1976-8257(pISSN)
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  • 2234-2753(eISSN)
한국독성학회 (Korean Society of Toxicology & Korea Environmental Mutagen Society)
권호 표지

랫드에 대한 G. bimaculatus의 급성경구독성시험

Acute Oral Toxicity of G. bimaculatus in Rats

  • 김인선 (성균관대학교 약학대학 독성학교실) ;
  • 안미영 (농업과학기술원 잠사곤충부) ;
  • 류강선 (농업과학기술원 잠사곤충부) ;
  • 이병무 (성균관대학교 약학대학 독성학교실)
  • 발행 : 2002.12.01
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초록

This study was carried out to investigate the acute toxicity of G. bimaculatus in Sprague-Dawley rats. G. bimaculatus was administered orally at doses of 8, 40, 200, 1000 and 5000 mg/kg. in this study, number of deaths, clinical sign, body weights, and pathological examination were investigated for 14 days after administration of G. bimaculatus. The results indicate that G. bimaculatus did not show any toxic effect in rats and oral $LD_{50}$ value was over 5000 mg/kg in Sprague-Dawley rats.

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참고문헌

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