Journal of Plant Biotechnology

The Korean Society of Plant Biotechnology (한국식물생명공학회)
권호 표지
DOI QR코드

DOI QR Code

Prospects for Plant Biotechnology and Bioindustry in the 21s1 Century: Paradigm Shift Driven by Genomics

21세기 식물생명공학과 생물산업의 전망 : 유전체 연구에 의한 Paradigm Shift

  • Liu, Jang-Ryol (Plant Cell Biotechnology Laboratory, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ;
  • Choi, Dong-Woog (Laboratory of Functional Genomics for Plant Secondary Metabolism (National Research Laboratory), Eugentech Inc.) ;
  • Chung, Hwa-Jee (Laboratory of Functional Genomics for Plant Secondary Metabolism (National Research Laboratory), Eugentech Inc.)
  • 유장렬 (한국생명공학연구원 식물세포공학연구실) ;
  • 최동욱 (한국생명공학연구원 식물세포공학연구실) ;
  • 정화지 (유진텍(주) 부설 연구소 식물이차대사의 기능유전체 연구실)
  • Published : 2002.09.01
Download PDF
⟨ Previous Next ⟩

Abstract

Biotechnology in the 21st century will be driven by three emerging technologies: genomics, high-throughput biology, and bioinformatics. These technologies are complementary to one another. A large number of economically important crops are currently subjected to whole genome sequencing. Functional genomics for determining the functions of the genes comprising the given plant genome is under progress by using various means including phenotyping data from transgenic mutants, gene expression profiling data from DNA microarrays, and metabolic profiling data from LC/mass analysis. The aim of plant molecular breeding is shifting from introducing agronomic traits such as herbicide and insect resistance to introducing quality traits such as healthful oils and proteins, which will lead to improved and nutritional food and feed products. Plant molecular breeding is also expected to aim to develop crops for producing human therapeutic and industrial proteins.

Keywords

References

  1. Anonymous (2000) http://www.monsanto.com/monsanto/ediacenter/background/Better.html
  2. Anonymous (2002a) http://www.phenomenon.com
  3. Anonymous (2002b) http://www.paradigmgenetics.com
  4. James C (1999) Global review of commercialized transgenic crops: 1999 ISAAA Briefs No. 12: Preview. IAAA: Ithaca, NY
  5. Lange BM, Wildung MR, Stauber EJ, Sanchez C, Pouchnik D, Croteau R (2000) Probing essential oil biosynthesis and secretion by functional evaluation of expressed sequence tags from mint glandular trichomes. Proc Natl Acad Sci USA 97:2934-2939 https://doi.org/10.1073/pnas.97.6.2934
  6. Moore GL, Maranas CD, Lutz S, Benkovic SJ (2001) Predicting crossover generation in DNA shuffling. Proc Natl Acad Sci USA 98:3226-3231 https://doi.org/10.1073/pnas.051631498
  7. Rifkin J (1998) The biotech century: harnessing the gene and remaking the world. Tarcher/Putnam 271 pp
  8. Staub JM, Garcia B, Graves J, Hajdukiewicz PTJ, Hunter P, Nehra N, Paradkar V, Schlittler M, Carroll JA, Spatola L, Ward D, Ye G, Russell DA (2000) High-yield production of a human therapeutic protein in tobacco chloroplasts. Nature Biotech 18:333-338 https://doi.org/10.1038/73796
  9. Stemmer WPC (1994) DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution. Proc Natl Acad Sci USA 91:10747-10751 https://doi.org/10.1073/pnas.91.22.10747
  10. Tomita M, Hashimoto K, Takahashi K, Shimizu T, Matsuzaki Y, Miyoshi F, Saito K, Tanida S, Yugi K, Venter JC, Hutchison, C (1999) E-CELL: Software environment for whole cell simulation. Bioinformatics 15:72-84 https://doi.org/10.1093/bioinformatics/15.1.72
  11. Ye X, AI-Babili S, Kloti A, Zhang J, Lucca P, Beyer P, Potrykus I (2000) Engineering the Provitamin A (${\beta}$-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm. Science: 303-305
  12. Yun, DJ, Hashimoto T, Yamada Y (1992) Metabolic engineering of medicinal plants: transgenic: Atropa belladonna with improved alkaloid composition. Proc Nat Acad Sci USA 89: 11799-11803 https://doi.org/10.1073/pnas.89.24.11799
  13. 유장렬, 정원중, 민성란, 정석원, 한수경 (2002) 미생물 리컴비네이즈를 이용한 색소체 형질전환 방법. 출원번호 10-2002-0000218