Aerobic Antimicrobial Susceptibility Patterns of Bacteria Isolated from Dogs

개에서 분리된 호기성 병원성 세균의 항생제 감수성

  • Hee Yoo (Department of Internal Medicine, College of Veterinary Medicine and School of Agrcultural Biotechnology) ;
  • Park, Se-Won (Department of Internal Medicine, College of Veterinary Medicine and School of Agrcultural Biotechnology) ;
  • Hwang, Cheol-Yong (Department of Internal Medicine, College of Veterinary Medicine and School of Agrcultural Biotechnology) ;
  • Youn, Hwa-Young (Department of Internal Medicine, College of Veterinary Medicine and School of Agrcultural Biotechnology) ;
  • Han, Hong-Ryul (Department of Internal Medicine, College of Veterinary Medicine and School of Agrcultural Biotechnology)
  • Published : 2002.09.01

Abstract

Isolation and identification of causative microorganisms and susceptibility testing are important in selecting appropriate antimicrobial agent. The purpose of this study was to determine the antimicrobial susceptibility patterns and identification of bacteria for the selection of a therapeutic antibiotic agent for treatment. Specimens were cultured aerobically from dog patients brought to the veterinary medical teaching hospital of Seoul National University between July 1999 and September 2000. A total of 157 isolates were from skin(63), urine(45), ear canal(31) and conjunctiva(18). The result is that the most common organisms isolated from dog patients were S. intermedius was the most common isolates from the skin, ear canal, and conjunctiva. E. coli was the most common isolated from urine. Most of gram-positive isolates were resistant to ampicillin(80.6%), erythromycin(68.8%), penicillin(86.2%), tetracycline(89.2%). Otherwise most of gam-negative isolates were resistant to ampicillin(73.4%), trimethoprim-sulfa(53.3%). E. coli was resistant to ciprofloxacin(61.5%), piperacillin (69.2%). Antimicrobial susceptibility pattern by the sampling site was not remarkably different except 5. aureus isolated from urine.

질병을 유발하는 세균의 분리와 동정, 그리고 그 세균에 대한 항생제 감수성 검사는 치료에 효과적인 항생제를 선택하는 데에 있어서 중요하다 본 연구의 목적은 항생제 감수성의 경향을 알아보고 치료를 위한 효과적인 항생제 선택을 위해 세균을 동정하는 것이었다. 1999년 7월부터 2000년 9월 사이에 서울대학교 수의과대학 부속동물병원에 내원한 개로부터 실험재료를 채취하여 호기배양을 실시하였다. 피부(63개), 뇨(45개), 외이도(31개), 안결막(18개)으로부터 채취한 총 157개 시료를 이용하였다 내원한 환자의 피부, 외이도, 결막에서 가장 많이 분리된 세균은 S. intermedius였다. 내원한 환자의 뇨에서 가장 많이 분리된 세균은 E. coli 였다. 분리된 그람 양성 세균의 대부분은 ampicillin(80.6%), erythromycin(68.8%), penicillin(86.2%), tetracycline(89.2%) 에 대해 저항성을 나타내었다. 반면, 분리된 그람 음성 세균의 대부분은 ampicillin(73.4%), trimethoprim-sulfa(53.3%) 에 대해 저항성을 나타내었다 E. coli는 ciprofloxacin(6l.5%), piperacillin(69.2%) 에 대해 저항성을 나타내었다 분리 동정된 세균의 채취부위에 따른 항생제 감수성의 차이는 뇨중의 S. aureus를 제외하고는 특이할 만한 사항이 없었다.

Keywords

References

  1. Vet Med Sm Anim Clin v.69 Culture and sensitivity test results from common canine and feline bacterial diseases Burke TJ;Strelow LW;Smith AR
  2. Am J Vet Res v.46 Comparison of coagulase test methods for identification of Staphylococcus intermedius from dogs Cox HU;Newman SS;Roy AF;Hoskins JD;Foil CS
  3. J Am Anim Hosp Assoc v.30 Antimicrobial Susceptibility of Selected Infectious Bacterial Agents Obtained From Dogs Hirsh DC;Jang SS
  4. Letters in Applied Microbiology v.22 Antibiotic sensitivity of Staphyococcus aureus and Staph. intermedius of canine and feline origin Hoekstra KA;Paulton RJ https://doi.org/10.1111/j.1472-765X.1996.tb01140.x
  5. J Am Vet Med Assoc v.210 Organisms isolated from dogs and cats with anaerobic infections and susceptibility to selected antimicrobial agents Jang SS;Breher JE;Dabaco LA;Hirsh DC
  6. Kirk's Current Veterinary Therapy VIII - Small Animal Practice Antimicrobial susceptibility tests for urinary tract pathogrns Ling GV;Hirsh DC
  7. J Am Vet Med Assoc v.185 Canine urinary tract infections : A comparison of in vitro antimicrobial susceptibility test results and response to oral therapy with ampicillin or with trimethoprim-sulfa Ling GV;Rohrich PJ;Ruby AL;Johnson DL;Jang SS
  8. Approved Standards M7-A3 Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. National Committee for Clinical Laboratory Standards
  9. J Clin Microbiol v.30 Evaluation of Methods for Differentiation of Coagulase-Positive Staphylococci Roberson JR;Fox LK;Hancock DD;Besser TE
  10. J Am Vet Med Asso v.183 In vitro susceptibilities of canine urinary bacteria to selected antimicrobial agents Rohrich PJ;Ling GV;Ruby AL;Jang SS;Johnson DL