Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Effect of Psyllium Husk, Pectin and Cellulose on the Lipid Concentrations and Hemobiochemical Enzymes in Rats

차전자피, 펙틴 및 셀룰로스 함유 식이를 급여한 흰쥐의 지질농도 및 임상생화학적 지표 효소에 미치는 영향

  • Published : 2002.10.01
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Abstract

This study investigated the effects of different kinds of dietary fibers, cellulose, psyllium husk, pectin and the Psyllium husk Plus Pectin, on the lipid concentration and hernobiochemical enzyme activity in male Sprague-Dawley rats. The experimental groups were divided into four groups : the cellulose group, the psyllium husk group, the pectin group and the psyllium husk Plus Pectin group. Dietary fiber was supplemented at 10% (w/w) levels in the diet. Body weight gain, food intake and relative tissue seight were not significantly different among the dietary groups. Concentrations of triglyceride and phospholipid of serum in the psyllium husk and the pectin groups were significantly lower than those of the cellulose and the psyllium husk plus pectin groups. Concentration of total cholesterol of serum in the psyllium husk plus pectin group was lower than other dietary groups. However, concentrations of triglyceride and phospholipid of liver in the psyllium husk and the pectin groups were significantly higher than those of the cellulose and the psyllium husk plus pectin groups. The hemobiochemical Parameters, total protein, albumin, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, alkaline phosphatase, lactate dehydrogenase and blood urea nitrogen in serum of the psyllium husk group were lower than other dietary groups. These results showed that dietary psyllium husk could have lowering effects on serum triglyceride concentration without any side effect of hemobiochemical enzyme activity in rats.

식이섬유소원인 셀룰로스, 차전자피 및 펙틴의 단독 또는 혼합 급여에 의한 Sprague-Dawley계 수컷 흰쥐의 지질 농도 및 임상생화학적 지표 효소에 미치는 영향을 검토하였다. 실험 식이군은 식이 섬유소원에 따라 셀룰로스 투여군, 차전자피 투여군, 펙틴 투여군 및 차전자피와 펙틴 혼합 투여군으로 나누었으며, 이들식이 섬유소원은반합성 식이에 10%(w/w) 수준으로 첨가하여 6주간 자유급여 시켰다. 체중 증가량, 식이 섭취량, 각 조직의 상대적 중량은 각 실험군간에 유의한 차이는 없었다. 차전자피 투여군 및 펙틴 투여군에서 혈청 중성지질 및 인지질 농도는 셀룰로스 투여군 및 차전자피와 펙틴 혼합 투여군보다 통계상 유의하게 낮게 나타났다. 혈청 총 콜레스테롤 농도는 차전자피와 펙틴 혼합 투여군이 다른 식이 투여군보다 감소경향을 나타내었다. 그러나 간장 중성지질 및 인지질 농도는 혈청 지질 농도와는 반대로 차전자피 투여군 및 펙틴 투여군보다 셀룰로스 투여군 및 차전자피와 펙틴 혼합 투여군에서 낮게 나타났다. 차전자피 투여군의 혈청 임상생 화학적 지표 효소 glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, alkaline phosphatase, lactate do hydrogenase 활성과 총단백질, albumin, blood urea nitrogen은 다른 식이 투여군보다 낮게 나타났다 이상의 결과로부터 식이 섬유소인 차전자피 급여는 혈청 임상생화학적 지표에 크게 영향을 미치지 않으면서 중성지질 농도를 낮추는 작용이 있는 것으로 나타났다.

Keywords

References

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