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The Pharmaceutical Society of Korea (대한약학회)
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The Crystal Structure of KR-27042, An Analgesic Capsaicinoid

  • Park, No-Sang (Korea Research Institute of Chemical Technology) ;
  • Kim, Yang-Bae (College of Pharmacy, Seoul National University) ;
  • Jeong, Eun-Ju (Institute of Science and Technology, Cheil Jedang Corporation) ;
  • Chung, Uoo-Tae (College of Pharmacy, Chungbuk National University) ;
  • Park, Il-Yeong (College of Pharmacy, Chungbuk National University)
  • Published : 2002.02.01
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Abstract

The crystal structure of KR-21042, N-(3-Phenylpropyl )-4-hydroxy-3-methoxyphenylacetamide, was determined by single crystal X-ray diffraction analysis. The compound was recrystallized from a mixture of ethylacetate and n-hexane in monoclinic, space group $P2_1/c$, with a = 16.622(1), b = 6.215(1), c = 15.802(1) ${\AA},{\;}{\beta}=104.97(1)$, and Z = 4 The calculated density is $1.261{\;}g/cm^3$The structure was solved by the direct method and refined by full matrix least-squares procedure to the fecal R value of 0.068 for 2332 observed reflections.

Keywords

References

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