초록
장기간의 홍삼복방제 투여가 혈중지질 및 체지방에 미치는 영향을 알아보고자 체지방율이 30% 이상인 여학생 28명을 대상으로 위약군(placebo group, n=7명), 홍삼복방제투여군(red-ginseng product administration group, n=7명), 운동군(exercise group, n:1평), 운동 및 홍삼복방제투여군(exercise and red-ginseng product administration group, n=7명) 등 네 집단으로 분류하여 12주간의 실험기간에 따른 TC, TG, HDL-C, LDL-C, 체중 및 체지방의 변화를 관찰하여 분석한 결과 다음과 같은 결론을 얻었다. TC, TG, LDL-C의 경우 실험 12주후 위약군을 제외한 모든 집단에서 유의한[홍삼복방제투여군(p<.001), 운동군(p<.01), 운동 및 홍삼복방제투여군(p<.001)] 감소를 보였다. HDL-C의 경우 실험 12주후 위약군을 제외한 모든 집단에서 유의하게[홍삼복방제투여군(p<.05), 운동군(p<.01), 운동 및 홍삼복방제투여군(p<.001)] 증가하였다. 체중, 체지방율, 체지방량의 경우 실험 12주후 위약군을 제외한 모든 집단에서 유의한[홍삼복방제투여군(p<.001), 운동군(p<.001), 운동 및 홍삼복방제투여군(p<.001)] 감소를 보였다. 제지방량의 경우 실험 12주후 위약군을 제외한 모든 집단에서 유의하게[홍삼복방제투여군(p<.05), 운동군(p<.001), 운동 및 흥삼복방제투여군(p<.001)] 증가하였다.
This study was done in order to evaluate the of effects on the blood lipid profiles, the body weight and body fat in 28 healthy female volunteers who had over 30% body fat by the long term intake of red ginseng product. Subjects were divided into four groups (placebo group n=7, red ginseng product group; n=7, exorcise group; n=7, exercise & red ginseng product group; n=7). Blood sampling and measuring of the body fat were taken by pre-treatment, 3 weeks, and after 12 weeks. Statistical techniques for data analysis were applied one-way ANOVA and repeated measures ANOVA. The 5% level of significance was used as the critical level for this study. In summary of results, total cholesterol, triglyceride and low density lipoproprotein cholesterol were reduced in three groups (red ginseng product group, p<0.001, exercise group, p<0.01 ; exercise & red ginseng product group, p<0.001) except placebo group. HDL-C was improved in three groups (red ginseng product group, p<0.05; exercise group, p<0.01; exercise & red ginseng product group, p<0.001) except placebo group. Body weight, percent body fat and body fat mass were reduced in three groups (red ginseng product group, p<0.01, exercise group, p<0.01 ; exercise & red ginseng product group, p<0.001) except placebo group. Finally, lean body mass was improved in three groups (red ginseng product group, p<0.05; exercise group, p<0.01; exercise & red ginseng product group, p<0.001) except placebo group.