The Journal of Korean Physical Therapy

  • 제14권2호
  • /
  • Pages.107-115
  • /
  • 2002
  • /
  • 1229-0475(pISSN)
  • /
  • 2287-156X(eISSN)
대한물리치료학회 (The Korean Society of Physical Therapy)
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초음파가 창상조직내 표피성장인자의 발현에 미치는 영향

The Effect of Ultrasound on Epidermal Growth Factor Expression in Rat Wound Tissue

  • 남기원 (대구대학교 대학원 재활과학과 물리치료전공) ;
  • 구현모 (대구대학교 대학원 재활과학과 물리치료전공) ;
  • 김석범 (대구대학교 대학원 재활과학과 물리치료전공) ;
  • 이선민 (대구대학교 대학원 재활과학과 물리치료전공) ;
  • 김진상 (대구대학교 재활과학대학 물리치료학과)
  • Nam Ki-Won (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Daegu University) ;
  • Ku Hyun-Mo (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Daegu University) ;
  • Kim Suk-Bum (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Daegu University) ;
  • Lee Sun-Min (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Daegu University) ;
  • Kim Jin-Sang (Department of Physical Therapy, College of Rehabilitation Science, Daegu University)
  • 발행 : 2002.06.01
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초록

This study was performed to investigate the effect of ultrasound irradiation on epidermal growth factor(EGF) expression in rat wound tissue. Skin wounds were created below 5mm to both sides of scapular inferior angle. The right wound was used experimental side and left was used control side. Ultrasound was irradiated pulse rate $20\%$, frequency 1MHz, intensity $0.5W/cm^2$ for 5 minutes during 3days. After sonication during 3 days, rats were sacrified. The expression of epidermal growth factor evaluated immunohistochemistry on mouse anti-EGF. In the control side, a little expression of EGF was observed at epidermis and dermis. In the experimental side, A strong immunostaining was seen at epidermis and dermis. This study suggests that ultrasound irradiation is effective on EGF expression in wound tissue.

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