The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
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Effects of Low Power Laser for the Expression of EGF after Muscle Crush Injury

저강도레이저 조사가 근육압좌손상 후 척수분절의 EGF 발현에 미치는 영향

  • Kim Souk-Boum (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Taegu University) ;
  • Kim Dong-Hyun (Department of Occupational Therapy, Sorabol College) ;
  • Nam Ki-Won (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Taegu University) ;
  • Lee Sun-Min (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Taegu University) ;
  • Kim Jin-Sang (Department of Physical Therapy, College of Rehabilitation Science, Taegu University)
  • 김석범 (대구대학교 대학원 재활과학과 물리치료전공) ;
  • 김동현 (서라벌대학 작업치료과) ;
  • 남기원 (대구대학교 대학원 재활과학과 물리치료전공) ;
  • 이선민 (대구대학교 대학원 재활과학과 물리치료전공) ;
  • 김진상 (대구대학교 재활과학대학 물리치료학과)
  • Published : 2002.06.01
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Abstract

Low energy laser irradiation(LELI) therapy in physical therapy is widespread but the mechanisms are not fully understood. The purpose of the present study was to examine the epidermal growth factor(EGF)'s expression within lumbar spinal cord which corresponding with crushed extensor digitorum longus(EDL) of rats after low-power laser irradiation applied. After a crushed injury on the right EDL, low-power laser irradiation was applied by using 2000mW, 2000Hz, 830nm GaAlAs(Gallium-aluminum-arsenide) semiconductor diode laser. The laser treatment was performed with 10 minutes daily for 3days. After EDL crush injury, EGF immunoreactive positive neurons in experimental group were progressively decreased from the first to third days. Especially 1 day subgroup is highly expressed in dorsal horn(Lamina I, II, III) and around of central cannal of spinal cord(Lamina VII). Control group was only expressed slightly at 3 days. This study suggests that LELI stimulate that release and migration of EGF in spinal cord, which distict to wound site, therfore promote wound healing of EDL crush injury.

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