Korean Journal of Clinical Pharmacy (한국임상약학회지)
- Volume 12 Issue 1
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- Pages.29-38
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- 2002
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- 1226-6051(pISSN)
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- 2508-786X(eISSN)
Drug Use Evaluation of Antihypertensive Agents by JNC VI Guidelines
고혈압 치료 지침 Vl에 의한 항고혈압제의 사용평가
- Kim, Kyung Hwa (Graduate School of Clinical Pharmacy, Sookmyung Women's University) ;
- Lee, Suk Hyang (Graduate School of Clinical Pharmacy, Sookmyung Women's University)
- Published : 2002.03.01
Abstract
Hypertension is an important public health problem because it increases the risk of stroke, angina, myocardial infarction, heart failure, and end-stage renal disease. If it is not actively treated, morbidity and mortality increase with hypertension-induced complications and quality of life decreases. This study was to evaluate the use of antihypertensive drugs and blood pressure changes and to compare algorithms chosen (or the 1st and 2nd line therapy of hypertension based on the JNC VI recommendations. The medical charts of 222 patients with essential hypertension at St. Vincent's Hospital in Suwon from January 1997 to January 2000 were reviewed retrospectively. Data collection and analysis included baseline BP underlying diseases and complications, administered antihypertensives, BP changes, changes of antihypertensive regimen, and adverse effects with treatments. As results, the higher BP the patients had, the more frequent they had target organ damages and clinical cardiovascular diseases. Mean duration to reduce blood pressure less than 140/90 mmHg was 8 weeks in